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关于蛋白质组学在慢性萎缩性胃炎中医证候中应用与实践的探讨
蔡宗宗1, 朱姣1, 安娜1, 何婷1, 代二庆2
1.天津中医药大学, 天津 300193;2.中国人民武装警察部队后勤学院附属医院, 天津 300162
摘要:
介绍了目前中医治疗慢性萎缩性胃炎(CAG)的研究前景,分析了CAG中医证候缺乏客观物质基础的现状,探讨了CAG中医证候客观化的思路和方法,提出运用蛋白质组学技术,以蛋白质组为切入点,筛选出可用于CAG各证型诊断和治疗的血清蛋白质谱,建立一个“证候-蛋白质表达谱”.
关键词:  慢性萎缩性胃炎  证候  蛋白质组学
DOI:10.11656/j.issn.1673-9043.2016.01.18
分类号:
基金项目:国家自然科学基金资助项目(81273745),天津市自然科学基金资助项目(11JCYBJC10900).
A Study on the application and practice of chronic atrophic gastritis TCM syndrome based on proteomics
CAI Zong-zong1, ZHU Jiao1, AN Na1, HE Ting1, DAI Er-qing2
1.Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Affiliated Hospital of Logistics University of Chinese People's Armed Police Forces, Tianjin 300162, China
Abstract:
The paper focuses on the current researches on chronic atrophic gastritis (CAG) and the situations that Traditional Chinese Medicine (TCM) syndrome-differentiated diagnosis lacks the basic substance. The methods to standardize the TCM syndrome differentiation of CAG are discussed and the application of proteomics in this regard is put forward. The methods to standardize the TCM syndrome differentiation of CAG are discussed and the application of proteomics in this regard is put forward, so as to build up a expression profile on TCM syndrome-differentiated diagnosis and relative protein.
Key words:  chronic atrophic gastritis  TCM syndrome differentiation  proteomics
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