| 摘要: |
| [目的] 对沙芥的化学成分进行系统研究，为蒙药的研发提供扎实的物质基础，促进沙产业发展。[方法] 利用多种色谱法，如正相硅胶、反相ODS、Sephadex LH-20及高效液相色谱等进行分离纯化，并通过理化性质及波谱分析鉴定化合物结构。[结果] 从沙芥70%乙醇提取物中分离鉴定了7个单体化合物，分别为β-谷甾醇（1）、胡萝卜素（2）、staphylionoside D（3）、TgSSTg（4）、乙基-α-D-果糖苷（5）、pinellic acid（6）、Z-咖啡酸硬脂醇酯（7）。[结论] 化合物3~7为首次从该属植物中分离得到。 |
| 关键词: 传统沙生蒙药 沙芥 化学成分 结构鉴定 |
| DOI：10.11656/j.issn.1673-9043.2019.01.19 |
| 分类号:R284 |
| 基金项目:国家自然科学基金面上项目（81673688）。 |
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| Study on the constituents of traditional arenicolous mongolian medicine Pugionium cornutum (L.) Gaerth. |
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SHI Wenzhong, HUANG Peijian, RUAN Jingya, YANG Shengcai, WANG Tao, ZHANG Yi
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Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China
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| Abstract: |
| [Objective] The paper is aim to study the constituents from P. cornutum systematically,and promote the development of sand industry and construct the green economy in China.[Methods] The chemical compounds were isolated through kinds of chromatorgraphies such as Sephadex LH-20,ODS,Silica gel and PHPLC chromatorgraphies and identified by chemical and spectral analysis (1H,13C NMR,1H 1H COSY,HMQC,HMBC,UV,IR,MS).[Results] Seven compounds were obtained and identified as β-sitosterol (1) daucosterol (2),staphylionoside D (3),TgSSTg (4) ethyl-α-D-fructofuranoside (5) pinellic acid (6) Z-octadecyl caffeate (7) respectively.[Conclusion] Compounds 3-7 were obtained from Pugionium genus firstly. |
| Key words: Traditional arenicolous mongolian medicine Pugionium cornutum (L.) Gaerth. chemical constituents structural identification |
