| 摘要: |
| [目的]对花生衣中的化学成分进行研究，为花生衣的系统研究和开发利用提供物质基础。[方法]采用正相硅胶等柱色谱及高效液相色谱法进行分离纯化，并通过理化性质与波谱分析相结合的技术鉴定化合物的结构。[结果]从花生衣50%乙醇提取物中分离鉴定12个单体成分，分别为对羟基苯甲酸（1）、原儿茶酸（2）、原儿茶酸甲酯（3）、原儿茶酸乙酯（4）、对香豆酸（5）、儿茶素（6）、表儿茶素（7）、rhodonidin A（8）、槲皮素（9）、异鼠李素-3-O-β-D-葡萄糖苷（10）、异鼠李素-3-O-芸香糖苷（11）、3'，5，7-trihydroxyisoflavone-4'-methoxy-3'-O-β-glucopyranoside（12）。[结论]其中8为首次从落花生属中分离得到，3为首次从该植物中分离得到的化合物。 |
| 关键词: 花生衣 化学成分 结构鉴定 |
| DOI：10.11656/j.issn.1673-9043.2019.02.18 |
| 分类号:R284.2 |
| 基金项目:国家自然科学基金面上项目（81673688）；"十三五"重大新药创制课题（2018ZX09711001-009-010）；中医药管理局中药标准化项目（2017-110108-83-03-001423）。 |
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| Study on the constituents of Arachis hypogaea Linn. |
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WANG Jianli, QU Lu, RUAN Jingya, SUN Fan, WANG Tao, ZHANG Yi
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Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China
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| Abstract: |
| [Objective] To study chemical constituents from Arachis hypogaea Linn. in order to systematic research and exploitation.[Methods] The chemical compounds were isolated through Silica gel and PHPLC column chromatorgraphies,and identified by chemical and spectral analysis (1H,13C NMR,1H-1H COSY,HMQC,HMBC,and MS).[Results] Twelve compounds were obtained and identified as p-hydroxybenzoic acid (1),protocatechuic acid (2),protocatechuic acid methyl ester (3),protocatechuic acid ethyl ester (4),p-coumaric acid (5),catechin (6),epicatechin (7),rhodonidin A (8),quercetin (9),isorhamnetin-3-O-β-D-glucoside (10),isorhamnetin-3-O-rutinoside (11),3',5,7-trihydroxyisoflavone-4'-methoxy-3'-O-β-glucopyranoside (12),respectively.[Conclusion] Compound 8 was obtained from Arachis genus firstly,3 was isolated from the plant for the first time. |
| Key words: Arachis hypogaea Linn. chemical constituents structural identification |
