基于脏腑理论探讨抑郁症心肾不交证与脑-肠轴的关系

Relationship between depression with heart-kidney disharmony syndrome and brain-gut axis based on the theory of zang-fu

关键词:  抑郁症  心肾不交  脑-肠轴  脏腑理论

Key words:  depression  heart-kidney disharmony  brain-gut axis  theory of zang-fu

摘要:

心肾不交证是抑郁症临床中常见的中医证型之一，以心火亢盛、肾精亏虚为重要的病机特点。脑-肠轴是实现大脑和肠道之间中枢神经系统和肠神经系统两大系统功能整合的重要通道，在抑郁症发病机制中发挥重要作用。西医学认为脑-肠轴是抑郁症发生发展的媒介，中医学则将抑郁症的病机演变责之于心肾及相应的脏腑。文章从脏腑关系探讨并阐释抑郁症心肾不交证与脑-肠轴的关系。

Abstract:

Heart-kidney disharmony syndromeis one of the common syndromes of the depression in clinic. It is characterized by the disease mechanism of heart-fire hyperactivityand kidney-essencedeficiency. As the link passage of brain and gut,brain-gut axis plays an import role in depression that can integrate the function between central and enteric nervous system. Western medicine thinks that brain-gut axis is the mediator of depression,while Chinese medicine believes that thepathogenesis of depression lies in the heart,kidney and the corresponding zang and fu. This article summarized the relationship between depression with heart-kidney disharmony syndrome and brain-gut axis based on the theory of zang-fu.