中药雾化治疗中重度肝经郁热型带状疱疹的疗效观察

Observation on therapeutic effect of atomization of traditional Chinese medicine on herpes zoster of moderate and severe liver meridian depression-heat type

关键词:  中药雾化  带状疱疹  中重度  肝经郁热型

Key words:  Chinese medicine aerosol atomization  herpes zoster  moderate to severe  liver meridian stagnated-heat type

摘要:

[目的] 观察对症治疗基础上辅助应用中药雾化治疗中重度肝经郁热型带状疱疹的临床疗效。[方法] 将60例中重度肝经郁热型带状疱疹住院患者随机分为治疗组和对照组，每组30例。对照组患者予带状疱疹临床诊疗路径对症治疗，治疗组在对照组基础上，于抗病毒疗程5 d结束时，配合中药雾化，方用自拟开腠止痛汤，连续干预皮损1周，以2 d为1个观察周期，观察4次，2组疗程均为12 d。统计并比较2组患者治疗前后临床症状积分，时效性指标，比较2组临床疗效和不良事件发生情况。[结果] 治疗组总有效率90.00%，明显高于对照组的73.33%（P<0.05）；治疗后治疗组脱痂时间、疼痛缓解时间与对照组相比明显缩短（P<0.05）；治疗后2组症状积分均较本组治疗前明显降低（P<0.01），治疗组明显低于对照组（P<0.05）；2组患者不良事件发生情况比较差异无统计学意义（P>0.05）。[结论] 中药雾化辅助治疗中重度带状疱疹临床疗效较好，值得进一步研究。

Abstract:

[Objective] To observe the clinical efficacy of traditional Chinese medicine aerosol atomization on herpes zoster with moderate or severe stagnation of Liver Meridian on the basis of symptomatic treatment.[Methods] Sixty patients with herpes zoster of moderate or severe stagnation of liver meridian were randomly divided into treatment group and control group,thirty cases in each group. The patients in the control group were given symptomatic treatment by clinical diagnosis and treatment pathway of herpes zoster. On the basis of the control group,at the end of 5 days of antiviral treatment,the patients in the treatment group were combined with traditional Chinese medicine atomization,prescribed Kaicou Zhitong Decoction,which continuously intervened the skin lesion for one week,with 2 days as an observation cycle,and observed four times. The two groups were treated for 12 days. Statistical analysis and comparison of the two groups before and after treatment of clinical symptoms score,timeliness indicators,clinical efficacy and adverse events were compared between the two groups.[Results] The total effective rate of the treatment group was 90.00%,which was significantly higher than that of the control group 73.33% (P<0.05);the scab removal time and pain relief time of the treatment group were significantly shorter than those of the control group (P< 0.05);the symptom scores of the two groups after treatment were significantly lower than those before treatment (P<0.01),and the treatment group was significantly lower than that of the control group (P<0.05);There was no significant difference in the occurrence of adverse events (P>0.05).[Conclusion] The clinical effect of traditional aerosol Chinese medicine atomization in the adjuvant treatment of moderate and severe herpes zoster is better,which deserves further study.