| 摘要: |
| 石胡荽，又名鹅不食草，是我国传统药用植物。研究表明，石胡荽中含有大量的倍半萜类化学成分，其中，有多种愈创木内酯型倍半萜已被证明具有抗炎、抗肿瘤、抗氧化活性及抗病毒活性等方面的生物活性。文章总结了植物石胡荽中已分离鉴定得到的33种倍半萜化合物的化学结构特征及其药理活性作用，为更加合理地利用石胡荽的植物资源提供参考依据。 |
| 关键词: 石胡荽 倍半萜 愈创木内酯型 |
| DOI：10.11656/j.issn.1673-9043.2020.04.21 |
| 分类号:R284 |
| 基金项目:国家重点研发计划项目（2018YFC1707904，2018YFC1707905）。 |
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| Research progress on chemical constituents of guaiacolide-type Sesquiterpenes from Centipeda minima |
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SHI Rui, HE Mingshuai, LYU Jialin, WANG Rongrong, JIANG Miaomiao
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Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 301617, China
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| Abstract: |
| Centipeda minima, also known as herba centipedae, is a traditional Chinese midicinal plant. The results show that Centipeda minima contains a large number of guaiactone sesquiterpenes and has anti-allergic, anti-inflammatory and anti-tumor activities. In this paper, the chemical structures characteristics and pharmacological activities of 33 sesquiterpenes isolated and identified from Centipeda minima were summarized in order to provide a reference basis for more rational utilization of plant resources of Centipeda minima. |
| Key words: Centipeda minima sesquiterpenes guaiactone |
