“助阳扶火”温灸针刺法联合清肠温中方治疗轻中度溃疡性结肠炎的临床研究

Therapeutic analysis of “warm yang and improve fire” moxibustion and acupuncture combined with Qingchang Wenzhong Formulation for treatment of mild-moderate ulcerative colitis patients

关键词:  温灸针刺  清肠温中方  溃疡性结肠炎

Key words:  warm moxibustion and acupuncture  Qingchang Wenzhong Formulation  ulcerative colitis

摘要:

[目的] 观察“助阳扶火”温灸针刺法联合清肠温中方治疗寒热错杂、湿热瘀阻型轻中度溃疡性结肠炎患者的临床疗效。[方法] 将60例轻中度溃疡性结肠炎患者随机分为针药组（30例）和中药组（30例）。针药组给予温灸针刺+清肠温中方配方颗粒，中药组给予清肠温中方配方颗粒，治疗2周。观察治疗前后两组患者症状积分、证候疗效、改良Mayo评分及炎症性肠病生活质量量表（IBDQ量表）积分变化。[结果] 两组最终共纳入合格病例52例，针药组22例，中药组30例，治疗后，两组症状积分、证候疗效、改良Mayo评分、IBDQ量表评分均较前有所改善，差异有统计学意义（P<0.05），治疗后两组各项评分及疗效比较，差异无统计学意义（P>0.05）。两组患者均无不良反应，针药组患者畏寒、纳差、恶心、呕吐等症状明显改善。[结论] “助阳扶火”温灸针刺法联合清肠温中方能够明显改善轻中度活动期溃疡性结肠炎患者的临床症状，降低疾病活动度，提高患者生活质量，并且针药联用较单用中药治疗在患者全身症状改善方面效果更明显。

Abstract:

[Objective] To observe the clinical effect of "warm yang and improve fire" moxibustion and acupuncture combined with Qingchang Wenzhong Formulation in the treatment of mild-moderate ulcerative colitis (UC) patients with cold-heat jumble and stagnation of damp-heat syndrome.[Methods] Sixty patients with mild-moderate UC were divided into acupuncture group (30 cases) and traditional Chinese medicine group (30 cases) according to the random number table method. The acupuncture group was given warm moxibustion and acupuncture and Qingchang Wenzhong Formulation granule,while the traditional Chinese medicine group was given Qingchang Wenzhong Formulation granule,and both of them were treated for 2 weeks. The changes of single symptom score,traditional Chinese medicine syndrome score,modified Mayo score and IBDQ scale before and after treatment were observed.[Results] Fifty two cases were enrolled by eliminating unqualified cases,twenty two cases in acupuncture group,30 cases in traditional Chinese medicine. After treatment,two groups of individual symptoms integral,traditional Chinese medicine syndrome integral,improved the Mayo score,IBDQ scale scores were improved from the previous,the difference was statistically significant (P<0.05). According to the score and curative effect comparison of the two groups after treatment,there was no statistically significant difference (P>0.05). The symptoms of chills,poor appetite,nausea and vomiting were significantly improved in the acupuncture group.[Conclusion] "Warm yang and improve fire" moxibustion and acupuncture combined with Qingchang Wenzhong Formulation can significantly improve the clinical symptoms,reduce the disease activity and improve the quality of life of UC patients and the combination of acupuncture and medicine has a more obvious effect on the improvement of patients' systemic symptoms than the single treatment with traditional Chinese medicine.