针刺得气对健康受试者脑功能反应影响的研究

Study on the effect of acupuncture deqi on functional response of healthy human brain

关键词:  针刺  得气  近红外脑功能成像  客观化

Key words:  acupuncture  deqi  fNIRS  objectification

摘要:

[目的] 探索针刺得气对受试者脑功能的影响，为客观表征针刺得气提供实验依据。[方法] 对30例健康受试者的手三里穴分别施行得气与不得气针刺操作，以视觉模拟评分（VAS）量表评价受试者主观得气感，并运用功能性近红外光谱（fNIRS）技术全程采集受试者脑功能信号，比较针刺得气与不得气时受试者的脑激活和脑连接情况；分析主观得气感与脑功能激活的相关性。[结果] 针刺得气激活了双侧额叶岛盖部、背外侧前额叶皮质区、左侧三角部及右侧额极区，使同侧顶叶和颞叶、左侧颞叶与右侧顶叶之间的脑功能连接增强；受试者得气感与脑功能反应具有相关性。[结论] 针刺得气可激活受试者双侧额叶，增强不同脑区间的功能连接性，受试者脑功能反应可能有助于客观表征针刺得气。

Abstract:

[Objective] To explore the effect of acupuncture deqi on brain function of acupuncture recipients,so as to provide experimental basis for objective characterization of acupuncture deqi.[Methods] The 30 healthy subjects were recruited and treated with deqi and Non-deqi operation respectively. The Vas scale was used to evaluate the subjective feeling of deqi,and the brain function signals of the subjects were collected by functional near infrared spectroscopy,compare the brain activation and brain connection of the recipient when deqi and Non-deqi;and correlation was analyzed with the subjective sensation of deqi.[Results] deqi significantly activated the insular part of bilateral frontal lobes,dorsolateral prefrontal cortex,left triangle and right frontal pole;the functional connections between ipsilateral parietal lobe and temporal lobe,left temporal lobe and right parietal lobe were significantly enhanced;and there is a correlation between deqi sensation and brain function response.[Conclusion] deqi significantly activate the bilateral frontal lobes of the acupuncture recipient and enhance the connectivity of brain function in different brain regions;the brain functional response of the recipient may be helpful to objectively characterize acupuncture deqi.