| 摘要: |
| 过敏性鼻炎发病受季节气候影响显著,具有秋季易感性,其具体病理机制尚未明确。文章基于中医"肺应秋"理论,联系气象环境变化对人体肺系的影响以及肺、鼻病理同源的特点,提出免疫-松果体轴对机体过敏免疫应答的节律性调节作用可能是过敏性鼻炎秋季易感的重要病理生理学基础。 |
| 关键词: 过敏性鼻炎 免疫-松果体轴 褪黑素 肺应秋 |
| DOI：10.11656/j.issn.1673-9043.2023.06.19 |
| 分类号:R276.1；R765.21 |
| 基金项目:国家自然科学基金项目（82174242）；天津市研究生科研创新项目（2021YJSS177）；天津中医药大学研究生科研创新项目（YJSKC-20212007）。 |
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| Study on the correlation between autumn susceptibility of allergic rhinitis and immune-pineal axis |
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LIANG Lijin, YUAN Weiling, LI Sheng, DU Xiaohang
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School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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| Abstract: |
| The incidence of allergic rhinitis is significantly affected by seasonal climate and is susceptible to autumn,which the specific pathological mechanism not clear yet. Based on the theory of "the lung corresponding to the autumn" in traditional Chinese medicine,combined with the influence of meteorological environment changes on human lung system and the homology of lung and nasal pathology,this paper proposed that the rhythm regulation of immune-pineal axis on allergic immune response may be an important pathophysiological basis of susceptibility to allergic rhinitis in autumn. |
| Key words: allergic rhinitis immune-pineal axis melatonin the lung corresponding to the autumn |
