| 摘要: |
| 两面针作为中国传统中药，常用于治疗跌打损伤，风湿痹痛，牙痛，胃痛等病症。两面针化学成分主要包括生物碱、香豆素、木脂素、黄酮等，具有抗炎镇痛、抗菌、抗肿瘤等药理活性。本文通过总结两面针化学成分、药理作用及质量控制的相关国内外文献，以期为两面针的临床研究和质量评价提供参考。 |
| 关键词: 两面针 氯化两面针碱 抗炎 抗肿瘤 |
| DOI：10.11656/j.issn.1673-9043.2024.02.11 |
| 分类号:R284；R285 |
| 基金项目:国家重点研发计划项目（2019YFC1711000）；天津市科技计划项目（21ZYJDJC00080）。 |
|
| Research advancement on chemical components,pharmacological effects and quality control of Zanthoxyli Radix |
|
WANG Shuangqi, WANG Yuan, LI Jin, HE Jun, MAO Haoping, CHANG Yanxu
|
|
State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
|
| Abstract: |
| As a traditional medicine in China,Zanthoxyli Radix is often used for treating traumatic injury,rheumatism pain,toothache,stomachache and other diseases. The chemical components of Zanthoxyli Radix mainly include alkaloids,coumarins,lignans,flavonoids,etc. Zanthoxyli Radix has many pharmacological activities such as anti-inflammatory,anti-bacterial and anti-tumor effect. In this paper,the chemical components,pharmacological effects and quality control of the Zanthoxyli Radix were summarized to provide references for the clinical study and quality evaluation of the Zanthoxyli Radix. |
| Key words: Zanthoxyli Radix nitidine chloride anti-inflammatory anti-tumor |
