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中医药治疗高催乳素血症研究进展
陈志雯1, 刘玉兰2, 高慧2, 郝艳红2, 徐立伟2, 王月2, 石祺雯1
1.承德医学院研究生院, 承德 067000;2.承德医学院附属医院中医科, 承德 067000
摘要:
西医研究认为高催乳素血症是临床妇科内分泌系统常见疾病,以腺垂体病变为主,表现为在下丘脑-垂体-性腺轴功能紊乱,临床以月经稀发、量少,甚至闭经,或伴溢乳、习惯性流产、不孕等症状多见。中医认为本病属于“闭经”“乳泣”“不孕症”等范畴,涉及脏腑以肝、脾、肾为主。西医治疗高催乳素血症的一线用药是多巴胺受体激动剂,毒副作用明显,且复发率高、难治愈,而通过中药、针灸等手段治疗效果显著,复发率低,预后良好。从目前临床应用来看,中医治疗高催乳素血症具有独特优势及良好发展前景。
关键词:  高催乳素血症  中医药治疗  作用机制  综述
DOI:10.11656/j.issn.1673-9043.2024.07.14
分类号:R271.9
基金项目:第五批全国中医临床优秀人才研修项目(国中医药人教函〔2022〕1号);河北省中医药管理局中医药类科研计划课题项目(2021200)。
A review of traditional Chinese medicine treatment of hyperprolactinemia
CHEN Zhiwen1, LIU Yulan2, GAO Hui2, HAO Yanhong2, XU Liwei2, WANG Yue2, SHI Qiwen1
1.Chengde Medical College Graduate School, Chengde 067000, China;2.Department of Traditional Chinese Medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China
Abstract:
Based on modern medical research,hyperprolactinemia is a common clinical endocrine disease,mainly adenohypophysial disease,reflected in the hypothalamic-pituitary-gonadal axis dysfunction,clinical symptoms of sporadic menstruation,small amount,and even amenorrhea,or accompanied by galactorrhea,habitual abortion,infertility and other symptoms. Traditional Chinese medicine(TCM) believes that the disease belongs to “amenorrhea” “lactate before childbirth” “infertility” and other categories,it mainly involves three viscera:liver,spleen and kidney. The first-line drug used in Western medicine to treat this disease is dopamine receptor agonist,which has obvious toxic side effects and high recurrence rate and is difficult to cure. However,Chinese medicine,acupuncture,massage and other means to treat this disease have significant curative effect,low recurrence rate and good prognosis. From the current clinical application,TCM treatment of hyperprolactinemia has its unique advantages and good prospects for development.
Key words:  hyperprolactinemia  traditional Chinese medicine treatment  action mechanism  review
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