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| 芪参益气滴丸治疗心脑血管疾病研究进展 |
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许光晶1,2,3, 姬艳苏4, 杨晴晴1, 郭鹏1, 王晓宇1,2,3, 金鑫1, 刘睿2,3
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1.武警后勤学院卫生勤务系, 天津 300309;2.天津中医药大学中药制药工程学院, 天津 301617;3.天津中医药大学现代中医药海河实验室, 天津 301617;4.武警特色医学中心药剂科, 天津 300162
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| 摘要: |
| 心血管疾病是全球致死和致残的主要原因。芪参益气滴丸由黄芪、丹参、三七和降香4味治疗心脑血管疾病常用中药配伍而成，具有抗炎、抗凋亡、抗血小板聚集及促进血管新生等药理作用。通过调节多靶点信号通路，为心脑血管疾病提供安全有效的治疗策略。文章综述芪参益气滴丸及其活性成分在心脑血管疾病中的药效学作用与分子机制，并探讨芪参益气滴丸在心脑血管疾病治疗方面的应用价值。 |
| 关键词: 芪参益气滴丸 心脑血管疾病 黄芪 丹参 三七 降香 |
| DOI：10.11656/j.issn.1673-9043.2026.01.13 |
| 分类号:R259 |
| 基金项目:武警部队高层次科技人才培养对象创新研究项目（ZZKY20222419）；天津市科技计划项目（24ZXZKSY00030）。 |
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| Research progress on Qishen Yiqi Dropping Pill in treating cardiovascular and cerebrovascular diseases |
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XU Guangjing1,2,3, JI Yansu4, YANG Qingqing1, GUO Peng1, WANG Xiaoyu1,2,3, JIN Xin1, LIU Rui2,3
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1.Department of Health Service, Logistics University of People's Armed Police Force, Tianjin 300309, China;2.School of Chinese Materia Medica Pharmaceutical Engineering, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;3.Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;4.Department of Pharmacy, Characteristic Medical Center of People's Armed Police Force, Tianjin 300162, China
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| Abstract: |
| Cardiovascular and cerebrovascular diseases are the leading cause of death and disability worldwide. Qishen Yiqi Dropping Pill（QSYQ），a traditional Chinese medicine formulation composed of four herbs：Astragali Radix（Huangqi），Salviae Miltiorrhizae Radix et Rhizoma（Danshen），Notoginseng Radix et Rhizoma（Sanqi），and Dalbergiae Odoriferae Lignum（Jiangxiang），is commonly used in treating such diseases. It exhibits pharmacological effects including anti-inflammatory，anti-apoptotic，anti-platelet aggregation，and pro-angiogenic activities. By regulating multiple target signaling pathways，QSYQ provides a safe and effective therapeutic strategy for cardiovascular and cerebrovascular diseases. The article reviews the pharmacodynamic effects and molecular mechanisms of QSYQ and its active components in cardiovascular and cerebrovascular diseases，and explores its application value in the treatment of these conditions. |
| Key words: Qishen Yiqi Dropping Pill cardiovascular and cerebrovascular diseases Astragali Radix Salviae Miltiorrhizae Radix et Rhizoma Notoginseng Radix et Rhizoma Dalbergiae Odoriferae Lignum |
