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| 针刺治疗脑卒中后痉挛性偏瘫的研究进展 |
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刘景岳1,2, 姜海伦1,2, 迟世浩1,2, 陶锋1,2, 邓士哲1, 孟智宏1
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1.天津中医药大学第一附属医院针灸部, 国家中医针灸临床医学研究中心, 天津 300193;2.天津中医药大学, 天津 301617
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| 摘要: |
| 脑卒中是导致中国伤残调整寿命年损失的主要原因之一, 其常见遗留症状包括痉挛性偏瘫。近年来针刺治疗脑卒中后痉挛性偏瘫的疗效已获得国内外广泛关注, 尽管针刺治疗该病效果肯定, 但其作用机制仍待进一步明确。文章通过论述针刺治疗脑卒中后痉挛性偏瘫的相关研究, 探讨针刺如何通过减少神经元凋亡、重塑皮质脊髓束、调节神经递质、降低脊髓前角运动元兴奋性、协调主动肌与拮抗肌等多种途径发挥作用, 并总结目前研究的不足之处, 旨在为将来针刺治疗该病的临床应用和科学研究提供建议。 |
| 关键词: 针刺 痉挛性偏瘫 神经元凋亡 皮质脊髓束 神经递质 脊髓前角运动元 主动肌与拮抗肌 |
| DOI：10.11656/j.issn.1673-9043.2025.09.12 |
| 分类号:R255.2 |
| 基金项目:国家自然科学基金项目(82374560);国家重点研发计划"醒脑开窍"康复方案治疗中风后运动性失语的循证研究项目(2018YFC1706001);国家中医针灸临床医学研究中心开放课题项目(NCRCOP2023003);天津中医药大学第一附属医院"拓新工程"基金项目(院XB2024002)。 |
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| Mechanism of acupuncture treatment of spastic hemiplegia after stroke |
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LIU Jingyue1,2, JIANG Hailun1,2, CHI Shihao1,2, TAO Feng1,2, DENG Shizhe1, MENG Zhihong1
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1.Department of Acupuncture, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China;2.Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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| Abstract: |
| Stroke is one of the major causes of disability-adjusted life-year loss in China, and its common residual symptoms include spastic hemiparesis. The efficacy of acupuncture in the treatment of spastic hemiplegia after stroke has gained wide attention at home and abroad in recent years. Although the effect of acupuncture in treating this disease is certain, its mechanism still needs to be further clarified. In this paper, we discuse the studies related to the treatment of spastic hemiparesis after stroke to investigate how acupuncture works by reduce neuronal apoptosis, remodel the corticospinal tract, regulate neurotransmitters, decrease excitability of motor elements in the anterior horn of the spinal cord and coordinate active and antagonist muscles, summarize the shortcomings of the current study to provide suggestions for future clinical application and scientific research. |
| Key words: acupuncture spastic hemiplegia neuronal apoptosis corticospinal tract neurotransmitter anterior horn motor elements of the spinal cord active and antagonist muscles |
