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平贝母水提物抗炎作用研究
黄丽晶1,2, 高文远1,2, 李霞2, 张艳军1
1.天津中医药大学中药学院 天津 300193;2.天津大学药物科学与技术学院 天津 300072
摘要:
[目的]观察平贝母水提物的抗炎作用。[方法]通过二甲苯致小鼠耳肿胀实验、蛋清致大鼠足趾肿胀实验及对小鼠毛细血管通透性的影响观察平贝母水提物的抗炎作用。[结论]平贝母水提物能减轻二甲苯所致的小鼠耳廓肿胀;能减轻蛋清所致大鼠足趾肿胀;降低小鼠毛细血管通透性。[结论]平贝母水提物具有抗炎作用。
关键词:  平贝母  水提物  抗炎作用
DOI:10.11656/j.issn.1672-1519.2009.06.22
分类号:
基金项目:国家科技部基础平台建设项目(2005DKA21000)
Anti-inflammatory effects of aqueous extract of bulbus fritillariae ussuriensis
HUANG Li-jing1,2, GAO Wen-yuan1,2, LI Xia2
1.School of Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China;2.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China
Abstract:
[Objective] To investigate the anti-inflammatory effects of aqueous extract of bulbus fritillariae ussuriensis. [Methods] Various inflammatory models, including the auricular edema induced by xylene in mice, the paw edema induced by albumen in rats and the permeability increase of blood capillary induced by acetic acid in mice were used to explore the anti-inflammation of aqueous extract of bulbus fritillariae ussuriensis. [Results] queous extract of bulbus fritillariae ussuriensis had good preventive action against the auricular edema induced by xylene, the paw edema induced by albumen and the permeability increase of blood capillary induced by acetic acid. [Conclusion] Aqueous extract of bulbus fritillariae ussuriensis has an anti-inflammatory effect.
Key words:  bulbus fritillariae ussuriensis  aqueous extract  anti-inflammatory effects
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