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| 复治菌阳肺结核中医证候分布规律研究 |
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张东1,2, 孙昕2, 刘恩顺3, 郑莉3, 杜钟珍2, 谢祎2
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1.天津中医药大学研究生院, 天津 300073;2.天津市海河医院, 天津市呼吸疾病研究所, 国家中医药管理局中医药防治传染病重点研究室, 天津 300350;3.天津中医药大学第二附属医院, 天津 300150
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| 摘要: |
| [目的] 探讨复治菌阳肺结核中医证候分布规律。[方法] 通过临床调查研究,收集362例复治菌阳肺结核患者的常见中医症状、体征及舌脉信息,采用Epidata3.02软件建立证候数据库,SPSS 18.0软件进行描述性分析和聚类分析。[结果] 证候出现频率最高的前4位是阴虚305例(84.25%),气虚212例(58.56%)、火热166例(45.86%)、瘀血133例(36.74%)。证候靶点出现频率最多的是肺、脾、肾。证候要素组合以2组、3组、4组证候组合情况最常见,聚类分析显示,气虚与阳虚聚为一类,火热、瘀血与痰浊聚为一类。[结论] 复治菌阳肺结核不仅具有传统的"阴虚火旺"证候特征,而且兼有脾、肾证候的比例明显上升,部分患者血瘀证表现明显。 |
| 关键词: 复治菌阳肺结核 证候分布 聚类分析 |
| DOI：10.11656/j.issn.1672-1519.2016.02.06 |
| 分类号: |
| 基金项目:天津市中医药管理局中医、中西医结合科研课题资助项目(11094)。 |
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| Research of the distribution law of traditional Chinese medicine syndromes in patients of retreatment pulmonary tuberculosis with smear-positive |
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Zhang Dong1,2, Sun Xin2, Liu En-shun3, Zheng Li3, Du Zhong-zhen2, Xie Yi2
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1.Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300073, China;2.Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Traditional Chinese Medicine Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China;3.The Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China
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| Abstract: |
| [Objective] Investigation on the distribution of traditional Chinese medicine(TCM) syndrome types of retreatment on smear positive pulmonary tuberculosis. [Methods] This is a multi center, large sample clinical research. To collected the common symptoms of TCM, physical signs, tongue and pulse examination from the 362 patients of retreatment smear positive pulmonary tuberculosis. Epidata3.02 software was used to build the database of TCM syndrome, SPSS 13.0 software for descriptive analysis and clustering analysis. [Results] According to the frequency of TCM syndrome, the most common was Yin-deficiency(305 cases, 84.25%), the second was Qi-deficiency(212 cases, 58.56%), next was fire-heat syndrome(166 cases, 45.86%), the fourth was blood-stasis(133 cases, 36.74%). The most common target of TCM syndrome were lung, spleen and kidney. The most common combination of syndrome factor was the second, third and the fourth TCM syndrome. The clustering analysis showed that the Qi-deficiency and the Yang-deficiency were copolymerized as the same category, the fire-heat syndrome, blood-stasis and phlegm-turbid were copolymerized as the another category. [Conclusion] The retreatment on smear positive pulmonary tuberculosis was not only characterised by "fire excess from Yin-deficiency" but also increased ratio of TCM syndrome combination of spleen and kidney. Some patients showed obvious blood-stasis syndrome. |
| Key words: smear positive pulmonary tuberculosis symptoms distribution clustering analysis |
