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柴胡疏肝散为主治疗胃食管反流病的Meta分析
郑敏1, 唐艳萍2
1.天津中医药大学2013级研究生, 天津 300193;2.天津市南开医院消化内科, 天津 300100
摘要:
[目的] 系统评价柴胡疏肝散为主治疗反流性胃食管病的临床疗效。[方法] 计算机检索维普数据库(VIP)、中国知识资源总库(CNKI)、万方数据库,纳入柴胡疏肝散为主治疗反流性食管炎的随机对照临床试验或半随机对照临床试验,检索时限均从建库至2015年6月,对纳入研究的方法学质量进行评价,用RevMan 5.3软件进行统计分析。[结果] Meta分析结果显示:与对照组相比,柴胡疏肝散为主治疗胃食管反流病在临床总有效率[OR=5.05,95%CI(4.04,6.32)]、胃镜下有效率[OR=3.67,95%CI(2.60,5.19)]及复发率[OR=0.50,95%CI(0.37,0.67)]方面具有优势,差异有统计学意义。[结论] 现有研究文献表明柴胡疏肝散治疗胃食管反流病在总有效率、内镜下有效率、复发率方面优于对照组。
关键词:  柴胡疏肝散  胃食管反流病  随机对照试验  系统评价
DOI:10.11656/j.issn.1672-1519.2016.08.03
分类号:
基金项目:
Meta analysis of Chaihu Shugan powder on gastroesophageal reflux disease
ZHENG Min1, TANG Yan-ping2
1.2013 Grade Postgraduate, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;2.Department of Gastroenterology, Tianjin Nankai Hospital, Tianjin 300100, China
Abstract:
[Objective] To estimate the clinical effect of gastroesophageal reflux disease treated by Chaihu Shugan powder primarily. [Methods] Randomized/quasi-randomized control trial retrieved from VIP database, Chain National Knowledge Infrastructure and WanFang database which gastroesophageal reflux disease treated by Chaihu Shugan powder primarily, from build library until June 2015 and objective the studies included in. RevMan 5.3 is used to analyze the study. [Results] Compared with the control group, it's has advantages in the clinical total effective rate[OR=5.05, 95%CI(4.04, 6.32)], gastroscope effect[OR=3.67, 95%CI(2.60, 5.19)] and recurrence rate[OR=0.50, 95%CI(0.37,0.67)], which have significant difference in angle statistics. [Conclusion] Researches proved that Chaihu Shugan powder treat gastroesophageal reflux diseases have advantages in clinical total effective rate,gastroscope effection and recurrence rate compared with the control group.
Key words:  Chaihu Shugan powder  gastroesophageal reflux disease  randomized control trial  system evaluation
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