蕲蛇治疗类风湿关节炎的临床研究

Clinical research of long-noded pit viper on rheumatoid arthritis

关键词:  蕲蛇  类风湿关节炎  临床研究

Key words:  long-noded pit viper  rheumatoid arthritis  clinical research

摘要:

[目的] 从临床角度来探讨蕲蛇治疗类风湿关节炎的作用机制。[方法] 选择符合ACR2009类风湿关节炎最新诊断标准患者60例，随机分为来氟米特组30例，蕲蛇组30例，治疗前及治疗1个月后分别详细检查记录风湿活动指标、免疫指标、凝血指标、症状指标，及DAS28评分，并进行比较和统计分析。[结果] 蕲蛇组无论是类风湿活动指标、免疫指标、临床症状指标、凝血指标及DAS28评分在治疗前后均有明显改善。在凝血指标、症状指标改善方面蕲蛇组还明显优于来氟米特组。[结论] 蕲蛇是从免疫调节、抗凝活血方面来改善类风湿关节炎的活动性。

Abstract:

[Objective] To study how does long-noded pit viper work in curing rheumatoid arthritis. [Methods] According to the latest diagnostic criteria of ACR2009 rheumatoid arthritis, 60 patients were selected and divided into two groups including 30 cases named leflunomide group and 30 cased named long-noded pit viper group. Evaluating indexes in rheumatic activity, immune system, clinical symptoms, cruor detection and DAS28 grade were recorded, compared and statistic analyzed before and a month later of treatments. [Results] The results demonstrated that long-noded pit viper group advanced the indexes ranging from before and after the treatment. Even compared to Leflunomide group, long-noded pit viper group was better in cruor detection and clinical symptom aspects. [Conclusion] Long-noded pit viper plays an important part in curing rheumatoid arthritis by immune system regulation and anti-coagulation in order to boost the mobility of rheumatoid arthritis.