加味玉屏风散治疗糖尿病肾病疗效观察

Curative effect observation of Jiawei Yupingfeng powder to diabetic nephropathy

关键词:  加味玉屏风散  糖尿病肾病  疗效观察

Key words:  Jiawei Yupingfeng powder  diabetic nephropathy  curative effect observation

摘要:

[目的] 研究加味玉屏风散治疗糖尿病肾病的治疗效果。[方法] 选择从2015年1-12月期间到本院肾病科进行治疗的患者80名，Ⅲ～Ⅴ期糖尿病肾病患者作为研究对象，将其随机分为治疗组与对照组，每组40例，对照组的患者采用常规基础疗法，治疗组患者在常规基础疗法的基础上加用中药加味玉屏风散，对比观察两组的治疗效果。[结果] 在血脂、肾功能及24 h尿蛋白定量方面，治疗组在治疗后与治疗前相比出现明显的改善（P<0.05），和对照组相比差异有统计学意义（P<0.05）；在空腹血糖、糖化血红蛋白方面，治疗组与对照组差异无统计学意义（P>0.05）；在改善糖尿病肾病临床症状方面，治疗组的总有效率为95.00%，而对照组为75.00%，两组比较差异有统计学意义（P<0.05）。[结论] 加味玉屏风散对于糖尿病肾病患者的临床症状有明显的改善作用，还能够对其血脂代谢紊乱情况进行调节，以及改善肾功能、减少尿蛋白。由此可表明加味玉屏风散在治疗糖尿病肾病上有确切的治疗效果。

Abstract:

[Objective] To discuss the therapeutic effect of Jiawei Yupingfeng powder to diabetic nephropathy. [Methods] Teh 80 patients who suffered from Ⅲ~Ⅴstage diabetic nephropathy during January to December in 2015, were divided randomly into treatment group and control group, 40 patients in each one. The control group use conventional basic therapy and in treatment group, besides basic therapy, Jiawei Yupingfeng powder was used additionally. [Results] In the terms of blood fat, renal function and 24 hours urinary protein quantization, the treatment group is improved than before treatment (P<0.05), and compared with control group also ameliorated obviously (P<0.05). In the terms of fasting plasma glucose and glycosylated hemoglobin, there was no significant difference between two groups (P>0.05). In improving the clinical symptoms of diabetic nephropathy, the total effective rate of treatment group was 95.00% as well as 75.00% of control group, which showed significant difference between them (P<0.05). [Conclusion] Jiawei Yupingfeng powder not only has a significant improvement in the clinical symptoms of diabetic nephropathy patients, but also can regulate the blood fat metabolism disorders, improve renal function, as well as reduce urinary protein, which showed that Jiawei Yupingfeng powder has a definite therapeutic effect on the treatment of diabetic nephropathy.