基于专家问卷调查的寻常型银屑病常见证候和证候要素研究

Study on common traditional Chinese medicine syndrome and syndrome elements of psoriasis vulgaris based on expert questionnaire

关键词:  寻常型银屑病  证候  证候要素  专家问卷调查法

Key words:  psoriasis vulgaris  syndrome  syndrome element  Delphi method

摘要:

[目的] 基于专家问卷调查法，探讨寻常型银屑病的常见证候和证候要素。[方法] 在前期文献研究、临床银屑病患者症状等数据分析的基础上，研制专家问卷，应用专家问卷调查法（Delphi法）对在北京6家三级甲等中医医院的46位皮肤科专家进行信函式专家问卷调查，利用Epidata3.1建立数据库，通过分析专家对寻常型银屑病证候、证候要素常见程度的变异系数、均数、累积百分比，探讨寻常型银屑病的常见证候和证候要素。[结果] 本次调查共发放专家问卷46份，回收问卷46份，回收率（积极系数）为100%。根据寻常型银屑病证候、证候要素常见程度的数据分析，按照累积百分比≥70%且变异系数≤0.35的原则，确定寻常型银屑病的常见证候为：血热证、血瘀证、血燥证、血热风燥证、血虚风燥证和湿热证；常见病位类证候要素为：血、肌肤、肝、脾、肺；常见病性类证候要素为：血热、热（火）、血瘀、血燥、风、湿。[结论] 专家问卷调查法能较好的达成专家共识。通过本研究确定了寻常型银屑病的常见证候和证候要素，为进一步建立寻常型银屑病基于证候要素的中医辨证标准提供了依据。

Abstract:

[Objective] To study the common traditional Chinese medicine (TCM) syndrome and syndrome elements of psoriasis vulgaris based on experts' investigation. [Methods] A questionnaire was designed according to the results of previous literature and clinical research. Based on Delphi method, it was conducted a questionnaire survey with 46 dermatology doctors in 6 specialist hospitals, established the Epidata database, analyzed the coefficient of variation (CV), the degree of the mean, the cumulative percent of the common TCM syndrome and syndrome elements of psoriasis vulgaris. [Results] The 46 questionnaires were sent to the experts and 46 questionnaires were retrieved. The activity coefficient was 100%. A syndrome or syndrome element with cumulative percent ≥70% and CV≤0.35 could be identified as a common syndrome or syndrome element of TCM. According to this principle, the common TCM syndrome of psoriasis vulgaris was blood heat syndrome, blood stasis syndrome, blood dryness syndrome, blood heat and wind dryness syndrome, dry because of blood deficiency syndrome and dampness and heat syndrome. Blood, skin, lung, spleen and liver were the common TCM syndrome elements of location of disease. Blood heat, heat, blood stasis, blood dryness, wind and dampness were the common TCM syndrome elements of nature of disease. [Conclusion] Delphi method is a good way to collect consensus opinions of experts. This study determined the common TCM syndrome and syndrome elements of psoriasis vulgaris, which can afford the foundation of further establishment of the syndrome diagnostic criteria based on the syndrome elements.