| 摘要: |
| [目的] 通过临床观察探究中药灌肠方青赤散治疗溃疡性结肠炎临床疗效。[方法] 将符合纳入标准41名患者随机分为2组，对照组为20例，治疗组为21例，对照组口服美沙拉嗪肠溶片治疗，治疗组在口服美沙拉嗪肠溶片基础上加用青赤散保留灌肠治疗，比较两组治疗前后主要临床症状及肠镜改变积分、疾病活动性总积分、临床疗效、C反应蛋白（CRP）及血沉（ESR）。[结果] 1）与治疗前相比较，治疗后两组在腹痛、大便次数、便血、肠镜改变及疾病活动性方面均有明显改善（P<0.05），并且治疗组优于对照组（P<0.05）。2）在临床疗效方面，治疗组总有效率优于对照组（P<0.05）。3）在CRP、ESR方面，两组治疗后均较治疗前降低（P<0.05）；与对照组比较，治疗组治疗后的CRP、ESR均低于对照组（P<0.05）。[结论] 青赤散保留灌肠治疗溃疡性结肠炎具有较好疗效，临床值得推广。 |
| 关键词: 青赤散 溃疡性结肠炎 保留灌肠 |
| DOI：10.11656/j.issn.1672-1519.2016.12.05 |
| 分类号: |
| 基金项目: |
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| Clinical observation on the treatment of ulcerative colitis by retention enema with Green and red powder combined with Mesalazin Enteric-coated tablets |
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ZHOU Zheng-hua, YUE Yan, WANG Wei, WANG Hong-xia, KANG Hong-chang, WEI Jing-jing, HU Xi-bao, JI Jian-bin
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The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| [Objective] To explore the clinical efficacy of traditional Chinese medicine enema with Green and red powder in the treatment of ulcerative colitis by clinical observation.[Methods] The 41 patients met the inclusion criteria were randomly divided into 2 groups,20 cases in treatment group and 21 cases in control group.The control group was treated with Mesalazin Enteric-coated tablets and treatment group was treated with Mesalazin Enteric-coated tablets plus retention enema with Green and red powder.The main clinical symptoms and endoscopic change integral,disease activity of total score,clinical efficacy,C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) of two groups were compared before and after treatment.[Results] 1)Compared with before treatment,the abdominal pain,stool frequency,stool,colonoscopy and disease activity of two groups were significantly improved after treatment (P<0.05),and the treatment group was better than control group (P<0.05).2)In clinical efficacy,the total effective rate of treatment group was better than control group (P<0.05).3)The ESR and CRP after treatment were lower than before treatment (P<0.05) in two groups.The ESR and CRP in treatment group were lower than control group (P<0.05) after treatment.[Conclusion] The retention enema with Green and red powder has good efficacy in the treatment of ulcerative colitis,and it is worth popularizing in clinic. |
| Key words: Green and red powder ulcerative colitis retention enema |
