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焦虑症发病机制的研究进展
陈兆斌, 张博, 刘秀敏, 黄树明
黑龙江中医药大学中医药研究院, 哈尔滨 150040
摘要:
随着社会生活节奏的加快,焦虑症的发病率逐年上升。焦虑症因其病因不明、致病因素较为复杂、发病机制尚不清楚,成为临床上治疗的难题之一。中医研究认为,本病基本病机为情志失调,肝失疏泄,气郁化火;现代研究焦虑症发病机制主要是从神经递质假说,神经内分泌功能紊乱假说以及免疫功能紊乱假说等方面进行解释,文章从中西医两个方面进行分别阐述,以拓宽对焦虑症的认识。
关键词:  焦虑症  发病机制  神经内分泌  神经递质
DOI:10.11656/j.issn.1672-1519.2018.04.21
分类号:R749.72
基金项目:国家自然科学基金项目(81603321);黑龙江省自然科学基金项目(H2016072)。
Research progress on the pathogenesis of anxiety
CHEN Zhaobin, ZHANG Bo, LIU Xiumin, HUANG Shuming
Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China
Abstract:
With the accelerated pace of social life, the incidence of anxiety disorders are increasing year by year. Up to now, anxiety disorder has become one of the problems of clinical treatment because of its etiology is unknown, more complicated risk factors and the pathogenesis of anxiety disorders is unclear. This paper reviews the progress in the research of the pathogenesis of anxiety disorders from neurotransmitter hypothesis, neuroendocrine dysfunction hypothesis and system dysfunction disorder hypothesis.
Key words:  anxiety  pathogenesis  neuroendocrine  neurotransmitter
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