佐金平木联合健脾化痰法治疗对多发性抽动症患儿β2-微球蛋白的影响

Effects of Zorkin flat wood jointed with spleen phlegm method combined treatment of children with tourette syndrome β2-microglobulin

关键词:  佐金平木  健脾化痰法  多发性抽动症  β2-微球蛋白

Key words:  Zorkin flat wood  spleen phlegm method  tourette syndrome  β2-microglobulin

摘要:

[目的]观察和评价分析佐金平木联合健脾化痰法联合治疗对多发性抽动症患儿β2-微球蛋白（β2-MG）的影响。[方法]选取2015年1月-2016年12月黑龙江中医药大学附属第一医院收治的140例患儿，分为中医辨证治疗组（简称治疗组）和多巴胺受体阻滞剂组（简称对照组），每组各70例。对照组患儿给予氟哌啶醇治疗，治疗组患儿给予佐金平木联合健脾化痰法治疗。在两组患儿治疗前和治疗1 a后用放射免疫法分别测定其血和尿的β2-MG，同时常规检测血尿素氮（BUN）、肌酐（Scr），并进行治疗前后比较。[结果]两组患儿血β2-MG、尿β2-MG浓度均较治疗前升高，差异有统计学意义（P<0.05），治疗组的升高幅度小于对照组（P<0.05）。治疗组患儿治疗前后血BUN浓度、血Scr浓度比较差异均无统计学意义（P>0.05）。[结论]应用佐金平木联合健脾化痰法治疗小儿多发性抽动症对小儿的血和尿β2-MG有一定的影响，加强治疗期间血和尿β2-MG动态检测有助于了解肾脏早期损害及监控治疗药物反应。

Abstract:

[Objective] To observe and evaluate the analysis Zorkin flat wood joint spleen phlegm method combination therapy for children with tourette syndrome β2-microglobulin effects.[Methods] From January 2015 to December 2016, 140 cases of our hospital, divided into the TCM syndrome differentiation treatment group (treatment group) and dopamine receptor blockers group (control group), each group of 70 cases. Children with the control group given haloperidol treatment, treatment group give children Zorkin flat wood joint spleen phlegm method combined treatment. In the two groups of children before and 1 year after treatment were determined by method its β2-MG, blood and urine routine at the same time detection of blood urea nitrogen (BUN), creatinine (Scr), and compared before and after treatment.[Results] Two groups of children with β2-blood, urine β2-MG concentration was increased. The difference was statistically significant (P<0.05). The treatment group's rise less than the control group (P<0.05). Treatment group before and after treatment in children with blood concentration of BUN, Scr concentration differences had no statistical significance (P>0.05).[Conclusion] Application of Zorkin flat wood joint spleen phlegm method combined treatment of infantile tourette syndrome on infantile blood and urine β2-MG has certain influence, strengthen treatment of blood and urine during β2-MG dynamic detection contributes to an understanding of the early kidney damage and monitoring treatment response.