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中药复方内、外治法治疗糖尿病周围神经病变研究进展
梁旭东1, 宋渊2, 张团庄1, 沈稼轩1, 乔靖1, 朱克玉1
1.甘肃中医药大学, 兰州 730030;2.甘肃省中医院手外科, 兰州 730050
摘要:
文章综述了糖尿病周围神经病变的定义、西医对其认识、中医病因病机、治则治法、辨证分型、实验研究概况,应用中药复方内治法在抑制炎症反应、抑制氧化应激、纠正代谢紊乱、改善微循环、抑制胶质细胞激活以及中药复方外治法治疗该病等方面的相关机制研究文献进行归纳与总结,希望为今后临床应用中药复方内、外治法治疗及研究糖尿病周围神经病变提供理论依据和新思路。
关键词:  糖尿病周围神经病变  作用机制  中药复方  内治法  外治法
DOI:10.11656/j.issn.1672-1519.2022.11.22
分类号:R587.1
基金项目:国家自然科学基金项目(81860863);甘肃省中医药管理局科研项目(GZKG-2021-51)。
Research progress of Chinese herbal compound internal treatment and external treatment for diabetes peripheral neuropathy
LIANG Xudong1, SONG Yuan2, ZHANG Tuanzhuang1, SHENG Jiaxuan1, QIAO Jing1, ZHU Keyu1
1.Gansu University of Traditional Chinese Medicine, Lanzhou 730030, China;2.Department of Hand Surgery, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
Abstract:
This article reviews the definition of diabetes peripheral neuropathy,its understanding of modern medicine,etiology and pathogenesis,traditional Chinese medicine treatment,dialectical classification and experimental research. The research literatures on the related mechanisms of the application of traditional Chinese medicine compound internal treatment in inhibiting inflammatory response, inhibiting oxidative stress,correcting metabolic disorders,improving microcirculation,inhibiting glial cell activation,and traditional Chinese medicine compound external treatment of the disease were summarized. It is hoped to provide theoretical basis and new ideas for clinical application of traditional Chinese medicine compound internal and external therapy and research on diabetic peripheral neuropathy in the future.
Key words:  diabetic peripheral neuropathy  mechanism of action  traditional Chinese medicine compound  internal therapy  external therapy
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