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活血化瘀类中药现代药理学研究进展
陈希西1,2, 韩嵩3, 樊根豪1,2, 张露丹1,2, 吕春晓1, 黄宇虹1
1.天津中医药大学第二附属医院, 天津 300250;2.天津中医药大学, 天津 301617;3.青岛黑卓博林置地有限公司, 青岛 266555
摘要:
活血化瘀类中药在临床中应用广泛。目前国内外对于活血化瘀类中药的研究主要集中于单味药或活性成分的药理活性及靶点,缺少清晰明了的归纳总结。为了明确与活血化瘀中药功效对应的现代药理学作用通路及靶点,文章系统地整理和总结国内外相关文献资料,对活血化瘀中药的相关药理学研究进行了综述,为活血化瘀类中药进一步开发应用提供参考依据。
关键词:  活血化瘀  中药  药理学  作用机制
DOI:10.11656/j.issn.1672-1519.2023.02.20
分类号:R285.5
基金项目:国家自然科学基金青年项目(81803930);国家自然科学基金面上项目(81273936)。
Research progress of modern pharmacology of traditional Chinese medicine for promoting blood circulation and removing stasis
CHEN Xixi1,2, HAN Song3, FAN Genhao1,2, ZHANG Ludan1,2, LYU Chunxiao1, HUANG Yuhong1
1.Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China;2.Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;3.Qingdao Heizhuo Bolin Land Co., Ltd., Qingdao 266555, China
Abstract:
The traditional Chinese medicine(TCM) of promoting blood circulation and removing blood stasis is widely used in clinic. At present,domestic and foreign researches on TCM of promoting blood circulation and removing stasis mainly focus on the pharmacological activity and target of single drug or active ingredient,lacking clear and clear summary. In order to define the corresponding to the efficacy of TCM for activating blood circulation of modern pharmacology action pathways and targets,this paper systematically and summarizes the related literature at home and abroad,the related pharmacological research of TCM for activating blood circulation were summarized,for promoting blood circulation to remove blood stasis type of traditional Chinese medicine provides some references for the further development and application.
Key words:  promoting blood circulation and removing blood stasis  traditional Chinese medicine  pharmacology  mechanism of action
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