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从“肝主疏泄”探析三叶片的降脂作用
钱伟强1, 徐宗佩1, 王敏2, 陈瑶1, 李玉红1,3,4
1.天津中医药大学, 天津 301617;2.上海中医药大学, 上海 201203;3.天津中医药大学中医药研究院, 天津 301617;4.组分中药国家重点实验室, 天津 301617
摘要:
“肝主疏泄”是中医藏象理论中的重要研究内容之一,中医学认为“肝主疏泄”在高脂血症的发病与治疗中起着至关重要的作用。三叶片源自张伯礼院士的临床常用方,具有较好的降脂作用。文章从“肝主疏泄”出发,从肝主疏泄的内涵、肝主疏泄的生理功能与高脂血症病因病机的相关性、三叶片与肝主疏泄的机制的相关性及三叶片降脂作用的现代研究依据等方面探析三叶片的降脂作用,以求为临床中使用三叶片治疗高脂血症提供理论依据,使中医理论更好地服务于临床。
关键词:  肝主疏泄  三叶片  高脂血症  降脂作用
DOI:10.11656/j.issn.1672-1519.2024.01.11
分类号:R972.6
基金项目:国家自然科学基金重点项目(81830112)。
To explore the lipid-lowering effect of Sanye Pill from “liver main dredging”
QIAN Weiqiang1, XU Zongpei1, WANG Min2, CHEN Yao1, LI Yuhong1,3,4
1.Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;2.Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;3.Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;4.State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617 China
Abstract:
“Liver main dredging” is one of the important research contents in the theory of zangfu organs in traditional Chinese medicine.It is believed that “liver main dredge” plays a crucial role in the pathogenesis and treatment of hyperlipidemia. Sanye Pill derived from academician ZHANG Boli's commonly used clinical prescription,has a good lipid lowering effect. Starting from “liver main drainage”,this paper analyzes the lipid-lowering effect of Sanye Pill from the aspects of the connotation of liver main drainage,the correlation between the physiological function of liver main drainage and the etiology and pathogenesis of hyperlipidemia,the correlation between Sanye Pill and the mechanism of liver main drainage,and the modern research basis of the lipid-lowering effect of Sanye Pill,so as to provide theoretical basis for the clinical use of Sanye Pill in the treatment of hyperlipidemia. So that the theory of traditional Chinese medicine can better serve the clinical practice.
Key words:  liver main dredging  Sanye Pill  hyperlipidemia  lipid-lowering effect
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