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从豁闭通腑法论治晚期肝癌
葛媛莎1,2, 许博文1,2, 李杰2, 王贺平2, 曹璐畅2
1.北京中医药大学, 北京 100029;2.中国中医科学院广安门医院肿瘤科, 北京 100053
摘要:
肝癌进展迅速、病死率高,探索其有效治疗方法为临床重要课题。针对晚期肝癌临床病机特征,作者将其聚焦于恶性肿瘤五期演变“闭”之阶段,从胆腑、胃肠腑、三焦腑及瘀血闭阻角度阐明其病机源流,并从疏肝利胆治黄闭、调胃畅肠治肠脑闭、宣主三焦治水闭、益气活血治瘀闭等角度以豁闭通腑法论治晚期肝癌,拓展了“豁闭清源”治法的内涵。
关键词:  晚期肝癌  五期演变    豁闭通腑  豁闭清源
DOI:10.11656/j.issn.1672-1519.2025.03.07
分类号:R735.7
基金项目:北京市科技计划课题(Z221100003522021)。
Discussion on the treatment of advanced liver cancer from the method of opening the closure and unblocking fu-organs
GE Yuansha1,2, XU Bowen1,2, LI Jie2, WANG Heping2, CAO Luchang2
1.Beijing University of Chinese Medicine, Beijing 100029, China;2.Oncology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
Abstract:
With the rapid progress and high mortality,it is an important clinical topic to explore the effective treatment of liver cancer. According to the clinical pathogenesis characteristics of advanced liver cancer,our research group focused on the “closure” phase of “five-phase evolution” of malignant tumor. Besides,we clarified its pathogenesis from the point of view of gallbladder,gastrointestinal,Sanjiao and blood stasis. And we discussed the “opening the closure and unblocking fu-organs” treatment of advanced liver cancer from the perspectives of soothing the liver and gallbladder to cure yellow closure,regulating stomach and intestine to cure intestinal cerebral atresia,promoting Sanjiao to cure water closure,and replenishing qi and activating blood circulation to cure blood stasis closure,which expanded the connotation of the treatment of “opening the closure and clearing the source”.
Key words:  advanced liver cancer  five-phase evolution  closure  opening the closure and unblocking fu-organs  opening the closure and clearing the source
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