| 摘要: |
| 糖尿病足溃疡（DFU）是糖尿病患者常见的并发症，创面愈合困难，给患者带来巨大的痛苦和经济负担。近年来研究发现，水凝胶具有良好的生物相容性、稳定的物理化学性质和载药功能，可联合中药等成分构建为多功能水凝胶，在糖尿病足创面修复领域具有较好的应用前景。文章通过综述含有中药的多功能水凝胶在糖尿病足创面修复中的应用，探讨其促进创面愈合的机制，旨在为糖尿病足创面修复多功能中药水凝胶的开发提供理论依据和参考。 |
| 关键词: 多功能水凝胶 中药 糖尿病足溃疡 创面修复 |
| DOI：10.11656/j.issn.1672-1519.2026.02.17 |
| 分类号:R587.2 |
| 基金项目:国家自然科学基金项目（81973854） |
|
| Research progress of multifunctional Chinese medicine hydrogel in diabetic foot wound healing |
|
LIU Guotao1,2, MENG Shengyong1,2, WANG Jun1,2
|
|
1.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China;2.National Clinical Research Center for Chinese Medicine, Tianjin 300381, China
|
| Abstract: |
| Diabetic foot ulcer (DFU) is a common complication in diabetic patients. It is difficult to heal the wound, which brings great pain and economic burden to the patients. In recent years, studies have found that hydrogels have good biocompatibility, stable physical and chemical properties and drug-loading function. They can be combined with traditional Chinese medicine and other components to construct multifunctional hydrogels, which have a good application prospect in the field of diabetic foot wound repair. In this paper, the application of multifunctional hydrogels containing traditional Chinese medicine in the repair of diabetic foot wounds was reviewed, and the mechanism of promoting wound healing was discussed, aiming to provide theoretical basis and reference for the development of multifunctional Chinese medicine hydrogels for diabetic foot wound healing. |
| Key words: multifunctional hydrogel traditional Chinese medicine diabetic foot ulcer wound healing |
