| 摘要: |
| 目的: 研究平哮合剂对哮喘豚鼠引喘潜伏期及气道炎性细胞浸润的影响。方法: 采用卵白蛋白致敏法制造动物模型,末次给药后24h记录诱喘潜伏时间,并行支气管肺泡灌洗用于细胞记数及分类。结果: 平哮合剂能显著延长哮喘豚鼠的诱喘潜伏期,与模型组相比P<0.05,并能明显减轻哮喘豚鼠气道内(EOS)的浸润,与模型组相比P<0.05。结论: 平哮合剂具有明确的平喘、抗炎作用。 |
| 关键词: 平哮合剂 哮喘 豚鼠 实验研究 |
| DOI：10.11656/j.issn.1673-9043.2002.03.35 |
| 分类号: |
| 基金项目: |
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| Experimental Research of Pingxiao Granule on Asthma Guinea Pigs |
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Hao Yueqin
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Nanjing University of TCM, Nanjing 210029, China
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| Abstract: |
| Objective: To study the influence of Pingxiao Granule on the incubation period of asthsma and the airway inflammatory cellular indiltration in guinea pigs.Methods: The asthma model was established by ovalbumin sensitization.Twenty-four hours after challenge,the incubatiod periods of asthma was recorded and the bronchoalveolar lavage was performed in order to examine the staff count and cytological classification.Results: Compared with model group,Pingxiao Granule could prolong the incubation period of asthma and relief the airway inflammatory cellular infiltration markedly,P<0.05.Conclusion: Pingxiao Granule has an obviously anti-asthmatic and anti-inflammatory action. |
| Key words: Pingxiao Granule asthma guinea pig experimental research |
