摘要: |
目的: 研究二至丸水提物、女贞子、墨旱莲的保肝作用。方法: 通过检测血清酶学指标,观察二至丸对四氯化碳肝损伤模型的保护作用。结果: 用药各组均具有降低丙氨酸氨基转移酶(ALT)作用,以二至丸超声水提液和水煎液作用最强,女贞子皂甙和墨旱莲乙酸乙酯提取物的混合物可作为复方保肝降酶的有效部位,但两者不同混合比例的保肝降酶作用应作进一步研究,以寻找最佳配比,达到最佳保肝效果。结论: 用药各组均具有保肝降酶作用,女贞子皂甙和墨旱莲乙酸乙酯提取物的混合物可作为二至丸复方的保肝降酶的有效部位。 |
关键词: 二至丸 丙氨酸氨基转移酶(ALT) 预防作用 保肝降酶 |
DOI:10.11656/j.issn.1673-9043.2002.03.36 |
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Preventive Effect of Erzhi Wan and Its Extract on ALT Elevation Caused by Carbon Tetrachlorida |
Dou Zhiying, Song Kun, Ding Anwei
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Tianjin University of Traditional Chinese Medicine 300193
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Abstract: |
Objective: To study the liver-protective effect of the extract of Erzhi Wan,Nüzhenzi and Han liancao. Methods: The liver-protective effect of the extract on liver lesion pattern made by carbon tetrach loride by testing serum index of exzymology was observed. Results: ALT could be reduced in each treatment group. Conclusion: Each treatment group has the function of protecting liver and decreasing ALT. |
Key words: Erzhi Wan ALT preventive effect protecting live and decreasing ALT |