两种家鸭高脂血症模型的建立与比较研究*

Estabilishment and comparison of two hyperlipidemia duck models

关键词:  家鸭高脂血症模型  造模方法  高糖饮食

Key words:  duck hyperlipidemia model  method of making model  taking more sugar in bite and sup

摘要:

[目的]建立家鸭高脂血症模型,比较高剂量短时间和低剂量长时间两种造模方法的优劣。[方法]采用分别给予家鸭高剂量[玉米96.7% 、调和油1.9% 、食盐1.4% 、禽用维生素0.1g(/kg·d),100g(/kg·d)]、短时间(28d)(简称模型Ⅰ组)和低剂量[配料同上,50g(/kg·d)]、长时间(49d)(简称模型Ⅱ组)方法建立模型,动态观察体质量、血清脂质、血糖。[结果]两组血清胆固醇(TC)、甘油三酯(TG)、血糖(GLU)均高于实验前,模型Ⅰ组血TG高于模型Ⅱ。[结论]两种方法均可建立高脂血症模型,而高剂量短时间造模方法从优于低剂量长时间造模方法。

Abstract:

[Objective] To investigate two methods to establish hyperlipidemia model and compare them which is better.[Methods] The ducks kf model I group were fed with high-dose high glucose diet (96.7% corn,edible blend oil 1.9%,salt 1.4%,avian vitamin 0.1g/(kg·d),28 days.The ducks of modelⅡgroup were fed with low-dose high glucose diet 50 g/(kg·d),49 days.The index of body weight,blood sugar,serum grease was observed.[Results] The blood sugar, serum cholesterol and serum triglyceride of the two model groups were higher than that of before experment.[Conclusion] Two methods can replicate the hyperlipidemia model successfully, but the modelⅠis better than the modelⅡ.