| 摘要: |
| [目的]开发可工业化生产的补骨脂中补骨脂酚的富集方法。[方法]实验采用大孔吸附树脂技术有针对性地富集补骨脂提取液中的补骨脂酚,并尽可能去除补骨脂素和异补骨脂素等香豆素类化合物。[结果]经过大孔吸附树脂处理,可以有效去除补骨脂素和异补骨脂素,补骨脂酚含量达到45.6%。[结论]大孔吸附树脂方法用于补骨脂中补骨脂酚的富集,可以避免现有技术使用大量有机溶剂的缺点,该方法有效成分转移率高,成本低。 |
| 关键词: 补骨脂 大孔吸附树脂 补骨脂酚 补骨脂素 异补骨脂素 |
| DOI：10.11656/j.issn.1673-9043.2012.02.12 |
| 分类号: |
| 基金项目:* 科技部国际合作项目(2008DFB30070);天津市高教科技发展基金一般项目(0090209) |
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| Research on akuchiol enriching method from Psoralea corylifolia L with macroporous adsorptive resin D101 |
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LIU Er-wei, WANG Jia-long, HAN Li-feng
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The TCM Research Institute, Tianjin University of TCM, TCM Chemistry and Analysis Key Laboratory of Tianjin, Tianjin 300193, China
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| Abstract: |
| [Objective] To establish an easier purification method for using in industrial manufacture of bakuchiol from Psoralea corylifolia L.[Methods] The experiment utilized the macroporous adsorptive resin to enhance bakuchiol content successfully and at the same time decrease the contents of psoralen and isopsoralen as much as possible.[Results] The experiment showed that the content of bakuchiol was 45.6%, while psoralen and isopsoralen were effectively removed by the macroporous adsorption resin.[Conclusion] Resin can be used for enriching the contents of bakuchiol from Psoralea corylifolia L successfully. This method has advantage of using less organic solvents and can obtain higher transfer rate. |
| Key words: Psoralea corylifolia L macroporous adsorptive resin bakuchiol psoralen isopsoralen |
