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加味苍耳子散在鼻内镜术后黏膜炎症恢复中的疗效观察
郑妮亚1, 唐月英2, 曾屹生1, 陈宇1, 张国庆1, 谢秀平1
1.广州市中医医院 510130;2.福建省第二人民医院 350003
摘要:
[目的]加味苍耳子散在鼻内镜术后鼻腔黏膜炎症恢复中的疗效观察。[方法]慢性鼻-鼻窦炎患者56例,随机分为试验组27例和对照组29例。鼻内镜术后试验组以加味苍耳子散口服,分别于术前、术后3个月、6个月观察两组黏膜炎症细胞数量、组织形态。[结果]术后3个月、6个月,试验组较对照组黏膜炎症细胞数目显著性减少(P<0.05)。术后3个月试验组较对照组黏膜下腺体、杯状细胞显著性减少(P<0.01)。术后6个月两组黏膜下腺体、杯状细胞比较无显著改变(P>0.05)。[结论]加味苍耳子散有利于术后黏膜炎症的减轻。
关键词:  加味苍耳子散  鼻窦炎术后  炎症细胞  组织形态
DOI:10.11656/j.issn.1673-9043.2012.03.05
分类号:
基金项目:
Curative effect of modified Cang’erzi powder in recovery of mucosal inflammation after endoscopic surgery of nose
ZHENG Ni-ya1, TANG Yue-ying2, ZENG Qi-sheng1, CHEN Yu1, ZHANG Guo-qing1, XIE Xiu-ping1
1.Department of ENT, Guangzhou Hospital of TCMy, Guangzhou 510130, China;2.The Second People's Hospital of Fujian Province, Fuzhou 350003, China
Abstract:
[Objective] To observe the effect of modified Cang'erzi powder in the recovery of mucosal inflammation in nose cavity after endoscopic surgery.[Methods] Fifty-six patients with chronic sinusitis were randomly divided into treatment group(27 cases)and control group(29 cases).The treatment group was given modified Cang'erzi powder after functional endoscopic sinus surgery.Three and six months later,the number of the inflammatory cells and histopathological morphology on the nose mucosa in both groups were observed.[Results] At 3 month or 6 month after operation,the number of inflammatory cells in treatment group was significantly decreased (P<0.05)when compared with control group.After 3 month of treatment,the number of goblet cells and submucosa glands in treatment group was significantly decreased compared with control group(P<0.01).After 6 month,however, the difference was no significance.[Conclusion] Modified Cang'erzisan powder can relieve the mucosal inflammation after functional endoscopic sinus surgery.
Key words:  modified Cang’erzi powder  sinusitis surgery  inflammatory cells  histomorphology
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