| 摘要: |
| [目的]对绵萆薢的化学成分进行研究。[方法]采用大孔吸附树脂、ODS、Sephadex LH-20等柱色谱及制备型高效液相色谱法对其所含化学成分进行分离、制备，并利用波谱学方法鉴定了结构。[结果]从绵萆薢提取物中分离鉴定了Tachioside（1）、Isotachioside（2）、3，5-二甲氧基熊果苷（3）、2，6-二甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷（4）、淫羊藿次苷D（2 5）、苯甲醇-O-β-D-吡喃葡萄糖苷（6）和腺苷（7）等7个单体成分。[结论]化合物1~3为首次从薯蓣属中分离得到，4~7为首次从该植物中分离得到。 |
| 关键词: 绵萆薢 化学成分 结构鉴定 |
| DOI：10.11656/j.issn.1673-9043.2016.05.13 |
| 分类号: |
| 基金项目:新世纪优秀人才支持计划资助项目（NCET-12-1069）；天津市高等学校创新团队培养计划资助项目（TD12-5033）。 |
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| Isolation and structural identification of constituents from Dioscoreae spongiosae Rhizoma |
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CHAO Li-ping, RUAN Jing-ya, LIU Yan-xia, HAN Li-feng, WANG Tao, ZHANG Yi
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Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China
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| Abstract: |
| [Objective] Study on chemical constituents of Dioscoreae spongiosae Rhizoma.[Methods] The chemical constituents were obtained by ODS, Sephadex LH-20 and PHPLC chromatorgraphy isolation, and identified by chemical and spectral analysis.[Results] The structures of seven comounds were elucidated to be tachioside (1), isotachioside (2), koaburaside (3), 2, 6-dimethoxy-4-hydroxyphenol-1-O-β-D-glucopyranoside (4), icariside D2 (5), benzyl alcohol O-β-D-glucopyranoside (6), and adenosine (7), respectively.[Conclusion] Compounds 1~3 were obtained from Dioscoreae genus firstly, and 4~7 was isolated from the plant for the first time. |
| Key words: Dioscoreae spongiosae Rhizoma chemical constituents structural identification |
