H型高血压病痰瘀互结证相关因素的临床分析

The clinical analysis of correlative factors of phlegm and blood stasis syndrome in hypertension

关键词:  H型高血压病  痰瘀互结证  相关性  危险因素  性别

Key words:  H-Hypertension  phlegm and blood syndrome  related  risk factors  sexuality

摘要:

[目的] 探讨H型高血压病痰瘀互结证与临床常见危险因素的相关性，探讨不同性别间多种相关危险因素间可能存在的差异。[方法] 选取高血压病合并高同型半胱氨酸血症（HHcy）患者215例，按中医证型分为两个亚组，痰瘀互结证组117例，非痰瘀互结证组98例（对照组）。分别测定同型半胱氨酸（Hcy）、甘油三酯（TG）、总胆固醇（TC）、载脂蛋白a（Lpa）、空腹血糖（FPG）、血尿酸（UA）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、体重指数（BMI）、腹围（AC），对各项检测结果进行统计学分析。[结果] 1）两组间在Hcy、TG、TC、Lpa、FPG、UA检测指标水平方面比较，差异无统计学意义（P>0.05），LDL、HDL、BMI、AC检测指标水平方面比较，差异有统计学意义（P<0.05）。2）两组男性患者对比，Hcy、TG、TC、Lpa、FPG、UA、HDL检测指标水平方面比较，差异无统计学意义（P>0.05），LDL、BMI、AC检测指标水平对比，差异有统计学意义（P<0.05），其中两组男性患者BMI指数比较，差异明显有统计学意义（P<0.01）。3）两组女性患者对比，Hcy、TG、TC、Lpa、UA、HDL、LDL、BMI、AC检测指标水平方面比较，差异无统计学意义（P>0.05），两组女性患者FPG水平比较，差异有统计学意义（P<0.05）。[结论] 1）LDL、HDL水平、肥胖（BMI≥28）可能是H型高血压病痰瘀互结证的相关危险因素。2）男性H型高血压病痰瘀互结证患者可能更易出现超重（25 < BMI < 28）或肥胖（BMI≥28）和LDL水平升高；而女性患者可能逐渐表现出空腹血糖（FPG）的改变。

Abstract:

[Objective] To investigate the correlation common risk factors of H-Hypertension phlegm and blood syndrome, and to explore the feasible differences between male and female.[Methods] The 215 H-Hypertension patients were divided into two subgroups according to Chinese medicine syndromes,group of phlegm and blood syndrome(n=117), group of non-phlegm and blood syndrome(n=98), calculating and comparing the statistics of Hcy, TG, TC, Lpa, FPG, UA, LDL, HDL, BMI index, AC among all groups, test results were statistically analyzed.[Results] 1)Two groups compared with TG, TC, Lpa, FPG, UA,the difference was not statistically significant(P>0.05),comparison of LDL, HDL, BMI, AC, the difference was statistics significance(P<0.05). 2)The groups of male patients compared with Hcy, TG, TC, Lpa, FPG, UA, HDL, the difference was not statistically significant(P>0.05), comparison of LDL, BMI, AC, the difference was statistically significant(P<0.05), in which two groups of male patients BMI index,significant differences were statistically significant(P<0.01). 3)The groups of male patients compared with Hcy, TG, TC, Lpa, UA, HDL, LDL, BMI, AC, the difference was not statistically significant(P>0.05), comparison of FPG,the difference was statistically significant (P<0.05).[Conclusion] 1)LDL, HDL, obesity(BMI≥28) may be the related risk factors of H-Hypertension in phlegm syndrome. 2)Overweight(25 < BMI < 28)or obesity(BMI≥28),elevated LDL may be the related risk factors of male in H-Hypertension phlegm syndrome,and elevated FPG levels may be the related risk factor of female in H-Hypertension phlegm syndrome.