| 摘要: |
| [目的]对白鲜皮中的脂肪酸类成分进行研究。[方法]采用正相硅胶等柱色谱及高效液相色谱手段进行分离纯化，并通过理化性质与波谱分析方法鉴定化合物的结构。[结果]从白鲜皮70%乙醇提取物中分离得到5个脂肪酸类单体成分，分别为亚油酸（1）、1-O-linoleoyl-glycerol（2）、油酸（3）、棕榈酸（4）、α-棕榈酸单甘油酯（5）。[结论]化合物2为首次从白鲜属中分离得到，化合物5为首次从该植物中分离得到的化合物。 |
| 关键词: 白鲜皮 脂肪酸 化学成分 结构鉴定 |
| DOI：10.11656/j.issn.1673-9043.2018.04.15 |
| 分类号:R284 |
| 基金项目:国家自然基金面上项目（NSFC 81673688）；新世纪优秀人才支持计划资助项（NCET-12-1069）。 |
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| Isolation and structural identification of fatty acids from Dictamnus dasycarpus Turcz |
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YANG Shengcai, WANG Jianli, LI Zheng, ZHENG Chang, WANG Tao, ZHANG Yi
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Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China
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| Abstract: |
| [Objective] To study fatty acids from the root bark of Dictamnus dasycarpus.[Methods] The chemical compounds were isolated through Silica gel column and PHPLC chromatorgraphies, and identified by chemical and spectral analysis (1H, 13C NMR, 1H-1H COSY, HMQC, HMBC, and MS).[Results] Five fatty acids were obtained and identified as linoleic acid (1), 1-O-linoleoyl-glycerol (2), oleic acid (3), palmitic acid (4), and glyceryl α-mono-palmitate (5), respectively.[Conclusion] Compound 2 was obtained from Dictamnus genus firstly, and compound 5 was isolated from the plant for the first time. |
| Key words: Dictamnus dasycarpus fatty acids chemical constituents structural identification |
