摘要: |
[目的]优选天麻的炮制工艺及其标准饮片的均匀化工艺。[方法]分析影响炮制和均匀化工艺的因素,在此基础上设计正交试验,分别以天麻素和对羟基苯甲醇总含量及总多糖含量、天麻素和对羟基苯甲醇总含量及出粉率为指标,综合优选出最佳炮制工艺和均匀化工艺。[结果]最佳润切工艺为:浸泡54 h,闷润22 h,切片后于60℃烘干;最佳蒸切工艺为:浸泡3 h,蒸制3 h,切片后于40℃烘干;最佳均匀化工艺:单次粉碎时间为15 s,粉碎3次,投料量占粉碎机总体积的3/4。[结论]通过验证实验证明优选出的最佳工艺稳定、合理、可行,可为天麻饮片的规范化研究提供参考。 |
关键词: 天麻 标准饮片 炮制工艺 均匀化工艺 正交试验 |
DOI:10.11656/j.issn.1673-9043.2018.06.14 |
分类号:R284.3 |
基金项目:国家发展改革委、中医药管理局中药标准化项目(ZYBZH-Y-SH-38);科技部基础性工作专项(2014FY111100)。 |
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Study on processing technology of Gastrodia elata Bl and homogenization technology of its standard pieces |
GAO Xiaoxiao1, LI Xia1, MIAO Jing1, SONG Yan2, ZHANG Yulian2, LV Tingting2, GAO Wenyuan1
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1.School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China;2.Research management department, Shanghai shangyao Huayu pharmaceutical co., ltd, Shanghai 200002, China
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Abstract: |
[Objective] To investigate the optimal processing technology of Gastrodia elata Bl and the optimal homogenization technology of its standard pieces.[Methods] The factors that affect the processing and homogenization technology were analyzed, orthogonal tests were designed on this basis. The total content of gastrodin and p-hydroxybenzyl alcohol and the content of polysaccharide, the total content of gastrodin and p-hydroxybenzyl alcohol and flour yield were as indexes to optimize the processing technology and homogenization technology, respectively.[Results] The optimized conditions of moistened pieces were soaking in water for 54 h, moistening for 22 h, slicing and drying at 60℃; The optimized conditions of steamed pieces were soaking in water for 3 h, steaming for 3 h, slicing and drying at 40℃; the optimal homogenization technology was selected as follows:3/4 volume of the pulverizer, running 15 s for 3 times.[Conclusion] The optimized technologies had been proved stable, reasonable and feasible through verification tests. And it provided a certain reference for the research of the standardization of Gastrodia elata Bl pieces. |
Key words: Gastrodia elata B1 standardized pieces processing technology homogenization technology orthogonal test |