胃三针结合健胃舒颗粒治疗脾虚气滞型功能性消化不良疗效观察

Clinical observation of Weisanzhen combined with Jianweisu granule for treatment of functional dyspepsia with spleen deficiency and qi stagnation

关键词:  功能性消化不良  胃三针  健胃舒颗粒  脾虚气滞证

Key words:  functional dyspepsia  Weisanzhen  Jianweisu granule  spleen deficiency and qi stagnation syndrome

摘要:

[目的] 探讨胃三针结合健胃舒颗粒治疗脾虚气滞型功能性消化不良的临床疗效。[方法] 将43例患者按随机数字表法分为治疗组22例和对照组21例。治疗组采用针刺中脘、足三里、内关，并口服健胃舒颗粒；对照组予枸橼酸莫沙必利口服。共治疗4周，观察和比较两组症状积分、疗效指数、水负荷试验和生活质量（SF-36）得分的差异变化。[结果] 治疗组的总有效率为86.36%，与对照组比较差异有统计学意义（P<0.05）；治疗后两组的症状积分均有下降，水负荷试验得分、生活质量得分均升高，组间比较，治疗组改善更明显，差异有统计学意义（P<0.05）。[结论] 胃三针结合健胃舒颗粒治疗脾虚气滞型FD症状改善明显，疗效确切，值得临床广泛推广。

Abstract:

[Objective] To explore the clinical efficacy of Weisanzhen combined with Jianweisu granule for Treatment of Functional Dyspepsia(FD) with spleen deficiency and qi stagnation. [Methods] Forty-two cases of patients were randomized into the treatment group Weisanzhen combined with Jianweisu granule and the control group(mosapride) according to the random number. both groups were treated by 4 courses and followed up for 4 weeks.the difference of score of digestion adverse symptoms, curative effect index, water load test's score and life quality(SF-36) were observed and compared. [Results] After 4 courses'treatment, the effective rate of treatment group was 86.36%, which showing no statistical significance difference(P<0.05).the dyspeptic symptom scores were significantly decreased in both group after treatment. The score of water load test and quality of life(SF-36) were better improved in the treatment group than those in the control group(P<0.05). [Conclusion] Weisanzhen combined with Jianweisu granule in the treatment of FD with spleen deficiency and qi stagnation can improve symptoms of dyspepsia, efficacy, and the quality of life, so it is worthy of wide clinical promotion.