| 摘要: |
| [目的] 对莫哈韦丝兰的化学成分进行系统研究。[方法] 利用正相硅胶、反相ODS、Sephadex LH-20及高效液相色谱等多种色谱法进行分离纯化，并通过理化性质及波谱分析鉴定化合物结构。[结果] 从莫哈韦丝兰70%乙醇提取物中分离鉴定了14个单体化合物，分别为咖啡酸（1）、β-羟基-3-甲氧基-4-羟基苯乙酮（2）、1-O-β-D-glu-copyranosyl-2-hydroxy-4-allylbenzene （3）、2-O-（4-hydroxybenzoyl）-2，4，6-trihydroxyphenylacetic acid （4）、对羟基苯甲酸（5）、原儿茶酸（6）、4-羟基-3-甲氧基苯甲酸（7）、丁香酸（8）、对羟基苯甲醛（9）、原儿茶醛（10）、麦芽酚（11）、5-hydroxymalto （l 12）、5-羟甲基糠醛（13）和4，4-二甲基-1，7-庚二酸（14）。[结论] 化合物2~4、7~14为首次从丝兰属植物中分离得到的化合物，5、6为首次从该种植物中分离得到的化合物。 |
| 关键词: 莫哈韦丝兰 化学成分 结构鉴定 |
| DOI：10.11656/j.issn.1673-9043.2019.03.18 |
| 分类号:R284 |
| 基金项目:国家自然科学基金面上项目资助（81673688）。 |
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| Study on the constituents of Yucca schidigera Roezl (Mojave) |
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QU Lu, WANG Jianli, HUANG Peijian, YAN Jiejing, WANG Tao, ZHANG Yi
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Tianjin University of Traditional Chinese Medicine, Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 301617, China
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| Abstract: |
| [Objective] The purpose of this thesis is to study the constituents from Y. schidigera systematically. [Methods] The silica gel, ODS, Sephadex LH-20 column chromatographies and preparative HPLC chromatography were used to conduct the isolation experiments, and the identifications of isolates were completed by the spectroscopic and chemical reaction methods.[Results] Fourteen compounds were obtained and identified as caffeic acid(1), β-hydroxypropiovanllone(2), 1-O-β-D-glucopyranosyl-2-hydroxy-4-allylbenzene(3), 2-O(4-hydroxybenzoyl)2, 4, 6-trihydroxyphenylacetic acid(4), p-hydroxyl benzoic acid(5), protocatechuic acid(6), 4-hydroxy-3-methoxybenzoic acid(7), syringic acid(8), p-hydroxy-benzaldehyde(9), protocatechuic aldehyde(10), maltol(11), 5hydroxymaltol(12), 5-hydroxy methyl furfura(13) and 4, 4-dimethyl-1, 7-pimelic acid(14), respectively. [Conclusion] Compounds 2-4, 7-14 were obtained from Yucca genus firstly, and compounds 5 and 6 were isolated from Y. schidigera for the first time. |
| Key words: Yucca schidigera Roezl(Mojave) chemical constituents structural identification |
