中医药治疗年龄相关性黄斑变性的用药规律

Medication regularity of traditional Chinese medicine in the treatment of age-related macular degeneration

关键词:  中药治疗  年龄相关性黄斑变性  中医传承辅助平台  数据挖掘

Key words:  Chinese medicine treatment  age-related macular degeneration  Traditional Chinese Medicine Inheritance Assistant Platform  data mining

摘要:

[目的] 初步探究中医药治疗年龄相关性黄斑变性的组方规律。[方法] 检索中医药治疗年龄相关性黄斑变性相关文献，筛选并建立数据库，进行方剂分析，挖掘出中医药治疗年龄相关性黄斑变性的组方规律，并得出新处方。[结果] 筛选出196首方剂，包含168味中药，分析得出高频次的药物为茯苓、当归、枸杞子、白术、丹参等，药物分类以补虚药、活血化瘀药、利水渗湿药等为主。得出34个常用药对，23组含有隐性规律的3味中药核心组合，4个新方组合。[结论] 年龄相关性黄斑变性的病因病机以肝、脾、肾3脏为本虚，痰、湿、热、瘀为标实。治则治法以补益肝肾、健脾益气、清热利湿、活血化瘀为基本大法。

Abstract:

[Objective] Preliminary study on the prescription and its regularity of treatment of age-related macular degeneration with traditional Chinese medicine.[Methods] To retrieve the literatures on treatment of age-related macular degeneration with traditional Chinese medicine,screen and establish a database,conduct prescription analysis,then excavate the prescription of Chinese medicine for age-related macular degeneration and the rule of the formula to obtain a new prescription.[Results] Screened out 196 prescriptions containing 168 herbs,through analysis and induction,it is concluded that the high-frequency herbs are Poria cocos,Ligusticum,Medlar,Mtractylodes,Salvia miltiorrhiza,Licorice,etc. The main classifications are tonify deficiency drugs,blood-activating and stasis-resolving drugs,diuretics for eliminating dampness.The etiology and pathogenesis of age-related macular degeneration is based on the deficiency of liver,spleen and kidney,and the sputum,dampness,heat and phlegm are the superficial causes.[Conclusion] The main treatment ways of age-related macular degeneration are tonifying the liver and kidney,nourishing qi to invigorate spleen,promoting blood circulation to remove blood stasis and clearing heat and eliminating dampness.