薄荷化学成分及药理活性研究进展

Research development of Menthae Haplocalycis Herba on chemical composition and pharmacological activity

关键词:  薄荷  化学成分  药理活性  毒性

Key words:  Menthae Haplocalycis Herba  chemical composition  pharmacology activity  toxicity

摘要:

薄荷是一味传统中药，具有疏散风热、清利头目、利咽透疹、疏肝行气等功效，临床上常用于风热感冒、头痛目赤、咽喉肿痛、喉痹、口疮、麻疹、风疹、胸胁胀闷等症的治疗。薄荷中的化学成分主要包括挥发油、黄酮类、萜类、酚酸类、醌类、苯丙素类等。现代药理研究表明，薄荷具有抗菌、抗病毒、抗炎、抗氧化、抗肿瘤、抗生育等药理活性。文章总结了近年来国内外有关薄荷化学成分、药理活性及毒性方面的相关文献，对其研究进展进行综述，为其治疗新型冠状病毒肺炎开发利用提供科学依据。

Abstract:

Menthae Haplocalycis Herba is one of traditional Chinese medicines with the effects of dispelling wind, antipyretics, diaphoretic, relieving pharyngeal vrash and soothing liver. It often used clinically for the treatment of wind-heat type common cold, headache, conjunctival congestion, sore throat, pharyngitis, aphthosis, measles, rubella, gas pains in chest and hypochondrium. The chemical components mainly include volatile oils, flavonoids, terpenoids, phenolic acid, quinones and phenylpropanoids. According to pharmacological studies, it has anti-bacterial, anti-virus, anti-inflammatory, anti-oxidation, anti-tumor and anti-fertility effects. This article summarized the domestic and foreign literature on chemical components, pharmacology activity and toxicity of Menthae Haplocalycis Herba in the past few years, and reviewed its research progress, providing new evidence for the reasonable development and utilization of Menthae Haplocalycis Herba on COVID-19.