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类风湿关节炎相关间质性肺病发病机制、诊断及治疗研究进展
王聪颖, 韩蕊, 李晶芳, 殷宏庆, 樊佳佳, 杨珍, 宋丽丽, 张艳军
天津中医药大学, 天津 301617
摘要:
类风湿关节炎(RA)是一种炎症性自身免疫疾病,主要影响关节还会影响其他身体组织。间质性肺病(ILD)是RA关节外表现较常见的一种疾病,可显著影响RA疾病的进展及预后。由于RA-ILD的致病因素及发病机制的复杂多样,以及缺乏特异性的诊断方法和明确的治疗手段,因此本文对RA-ILD的致病因素、发病机制、诊断及治疗的相关文献进行归纳与总结,以期为临床治疗提供参考。
关键词:  类风湿关节炎  间质性肺病  发病机制  诊断  治疗  研究进展
DOI:10.11656/j.issn.1673-9043.2022.02.25
分类号:R593.22
基金项目:国家自然科学基金项目(81803961);国家重点研发计划项目(2018YFC1706804)。
Research progress in the pathogenesis,diagnosis and treatment of rheumatoid arthritis-related interstitial lung disease
WANG Congying, HAN Rui, Li Jingfang, YIN Hongqing, FAN Jiajia, YANG Zhen, SONG Lili, ZHANG Yanjun
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Abstract:
Rheumatoid arthritis(RA) is an inflammatory autoimmune disease that mainly affects joints and other body tissues. Interstitial lung disease(ILD) is a common disease with extra-articular manifestations of RA,which can significantly affect the progression and prognosis of RA. Due to the complexity and diversity of the pathogenic factors and pathogenesis of RA-ILD,as well as the lack of specific diagnostic methods and clear treatment methods,this article summarizes the related literature on the pathogenic factors,pathogenesis,diagnosis and treatment of RA-ILD in order to provide reference for clinical treatment.
Key words:  rheumatoid arthritis  interstitial lung disease  pathogenesis  diagnosis  treatment  research progress
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