摘要: |
类风湿关节炎(RA)是一种炎症性自身免疫疾病,主要影响关节还会影响其他身体组织。间质性肺病(ILD)是RA关节外表现较常见的一种疾病,可显著影响RA疾病的进展及预后。由于RA-ILD的致病因素及发病机制的复杂多样,以及缺乏特异性的诊断方法和明确的治疗手段,因此本文对RA-ILD的致病因素、发病机制、诊断及治疗的相关文献进行归纳与总结,以期为临床治疗提供参考。 |
关键词: 类风湿关节炎 间质性肺病 发病机制 诊断 治疗 研究进展 |
DOI:10.11656/j.issn.1673-9043.2022.02.25 |
分类号:R593.22 |
基金项目:国家自然科学基金项目(81803961);国家重点研发计划项目(2018YFC1706804)。 |
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Research progress in the pathogenesis,diagnosis and treatment of rheumatoid arthritis-related interstitial lung disease |
WANG Congying, HAN Rui, Li Jingfang, YIN Hongqing, FAN Jiajia, YANG Zhen, SONG Lili, ZHANG Yanjun
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Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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Abstract: |
Rheumatoid arthritis(RA) is an inflammatory autoimmune disease that mainly affects joints and other body tissues. Interstitial lung disease(ILD) is a common disease with extra-articular manifestations of RA,which can significantly affect the progression and prognosis of RA. Due to the complexity and diversity of the pathogenic factors and pathogenesis of RA-ILD,as well as the lack of specific diagnostic methods and clear treatment methods,this article summarizes the related literature on the pathogenic factors,pathogenesis,diagnosis and treatment of RA-ILD in order to provide reference for clinical treatment. |
Key words: rheumatoid arthritis interstitial lung disease pathogenesis diagnosis treatment research progress |