| 本文已被：浏览 583次 下载 797次 |
码上扫一扫！ |
|
|
| 紫珠属药用植物研究进展及质量标志物预测分析 |
|
朱利婉1,2, 周利2, 李翔2, 李伟3,4, 黄胜4, 康利平1,2
|
|
1.天津中医药大学, 天津 301617;2.中国中医科学院中药资源中心道地药材国家重点实验室培育基地, 北京 100700;3.海南九芝堂药业有限公司, 海口 570311;4.九芝堂股份有限公司, 长沙 410205
|
|
| 摘要: |
| 紫珠属药用植物资源丰富，具有良好的药用价值，并在临床中广泛使用。药用紫珠属植物中主要含有苯乙醇苷类、黄酮类、环烯醚萜苷类等化学成分，具有止血，抗炎，抗氧化，抗肿瘤等药理作用。该文章系统总结了药用紫珠属的化学成分、药理作用研究进展并对其质量标志物（Q-Marker）进行分析，预测毛蕊花糖苷，异毛蕊花糖苷，连翘酯苷B，木犀草苷，木犀草素，芹菜素，槲皮素，verbascoside，金石蚕苷等可作为药用紫珠属植物的主要Q-Marker，为紫珠属植物质量评价体系的建立和进一步研究开发提供科学依据。 |
| 关键词: 紫珠属 化学成分 药理作用 Q-Marker 苯乙醇苷 黄酮 |
| DOI：10.11656/j.issn.1673-9043.2023.02.20 |
| 分类号:R284 |
| 基金项目:中国中医科学院科技创新工程项目（CI2021A05206）；国家重点研发计划项目（2020YFC1712700）。 |
|
| Research progress of the Callicarpa L. and predictive analysis on its quality marker |
|
ZHU Liwan1,2, ZHOU Li2, LI Xiang2, LI Wei3,4, HUANG Sheng4, KANG Li-ping1,2
|
|
1.Tianjin University of Chinese Medicine, Tianjin 301617, China;2.State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;3.Hainan Jiuzhitang Pharmaceutical Co., Ltd., Haikou 570311, China;4.Jiuzhitang Co., Ltd., Changsha 410205, China
|
| Abstract: |
| The medicinal plants of Callicarpa L. are rich in resources, has good medicinal value, and is widely used in clinic. It mainly contains phenylethanoids, flavonoids, iridoid glycosides and other chemical constituents, with hemostatic, anti-inflammatory, anti-oxidation, anti-tumor and other pharmacological effects. This paper systematically summarizes the research progress on the chemical composition, pharmacological action of four kinds of medicinal Callicarpa L. and its quality markers (Q-Markers) were predicted and analyzed acteoside, isoacteoside, forsythoside B, luteoloside, luteolin, apigenin, quercetin, verbascoside, poliumoside, etc. can be used as the main Q-Marker of Callicarpa L., in order to provide reference for the establishment of quality evaluation system, further research, comprehensive utilization and development of Callicarpa L.. |
| Key words: Callicarpa L. chemical constituent pharmacological activities quality marker phenylethanoids flavonoids |
