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扶正针刺法调控肠道微生态改善缺血性脑卒中恢复期神经功能作用机制研究进展
李舒婷1, 王亚男1, 刘沐东1, 马兰英1, 张贤一1, 赵海军1,2
1.山东中医药大学中医学院, 济南 250355;2.山东中医药大学山东省经典名方协同创新中心, 济南 250355
摘要:
缺血性脑卒中(IS)是严重威胁人类身心健康的常见脑血管疾病,给患者及家庭造成了严重的心理和经济负担。随着对该疾病的持续研究,发现针刺疗法能够改善IS恢复期患者的神经功能损伤,并有助于病情的预后和转归。近年来,关于肠道微生态与脑部疾病的相互影响被深入研究,文章基于中医“扶正”治则,结合肠道微生态探讨针刺在IS恢复期的作用机制,认为肠道菌群可通过调节免疫、神经系统以及肠道屏障通透性等方面影响大脑功能,针刺可从修复肠道屏障功能、调控肠道代谢及炎症因子等方面改善IS恢复期的预后及转归,以期为IS恢复期的临床诊治和科研提供新思路。
关键词:  缺血性脑卒中恢复期  肠道微生态  针刺  扶正
DOI:10.11656/j.issn.1673-9043.2025.02.12
分类号:R245.3;R743.32
基金项目:国家自然科学基金面上项目(82474660,81874411);山东自然科学基金创新发展联合基金项目(ZR2021LZY014)。
Progress of the mechanism of action of Fuzheng acupuncture method in regulating intestinal microecology to improve neurological function during recovery from ischemic stroke
LI Shuting1, WANG Yanan1, LIU Mudong1, MA Lanying1, ZHANG Xianyi1, ZHAO Haijun1,2
1.School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;2.Shandong Classic Formulas Collaborative Innovation Center, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
Abstract:
Ischemic stroke(IS) is a common cerebrovascular disease that seriously threatens the physical and mental health of human beings,causing serious psychological and economic burdens to patients and families. With the continuous research on this disease,it has been found that acupuncture therapy can improve the neurological impairment of patients recovering from IS and contribute to the prognosis and regression of the condition. In recent years,the interaction between intestinal microecology and brain diseases has been deeply studied. Based on the Chinese medicine principle of "supporting the right",the article explores the mechanism of acupuncture in IS recovery by combining with intestinal microecology,and concludes that intestinal flora can affect brain function by regulating the immune system,nervous system,and intestinal barrier permeability,etc. Acupuncture can be effective in repairing the intestinal barrier function,regulating the intestinal barrier function,and regulating the intestinal barrier permeability. Acupuncture can improve the prognosis and regression of IS recovery by repairing the intestinal barrier function,regulating intestinal metabolism and inflammatory factors,etc.,with a view to providing new ideas for clinical diagnosis and treatment and scientific research in IS recovery.
Key words:  ischemic stroke recovery period  intestinal microecology  acupuncture  supporting positive energy
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