| 摘要: |
| 痛风是由于机体嘌呤代谢异常和（或）尿酸排泄障碍引起的一种代谢性疾病。黄酮类化合物广泛存在于自然界中，有着良好的抗痛风作用。通过查阅国内外最新相关文献报道，文章对黄酮类化合物抗痛风作用及作用机制的研究进展进行综述，以期为新药研发和中医药临床治疗提供更加有力的理论支持。 |
| 关键词: 黄酮类化合物 痛风 作用机制 研究进展 |
| DOI：10.11656/j.issn.1673-9043.2025.02.14 |
| 分类号:R285.5;R589.7 |
| 基金项目:国家自然科学基金面上项目（82074377，82305202）;国家中医药管理局中医药传承与创新“百千万”人才工程（岐黄工程）岐黄学者项目;全国名老中医药专家传承工作室项目（975022）。 |
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| Research progress on the anti gout effect and mechanism of action of flavonoids |
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ZHAO Yuxing1,2, LIU Wei1,2
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1.The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China;2.National Clinical Research Center of Acupuncture and Moxibustion, Tianjin 300381, China
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| Abstract: |
| Gout is a metabolic rheumatic disease caused by abnormal purine metabolism and/or impaired uric acid excretion in the body. Flavonoids are widely present in nature and have good anti gout effects. By reviewing the latest relevant literature reports at home and abroad,this article reviews the research progress on the anti gout effects and mechanisms of flavonoids,in order to provide more powerful theoretical support for the development of new drugs and clinical treatment of traditional Chinese medicine. |
| Key words: flavonoids gout mechanism of action research progress |
