| 摘要: |
| 大皂角是中国的传统中药，主要含有三萜皂苷、木脂素、氨基酸类化学成分，具有抗肿瘤、抗氧化、抗高脂血症、抗人类免疫缺陷病毒（HIV）、抗菌和抗病毒等多种药理作用，临床上常用于支气管哮喘、支气管扩张等肺部疾病。本文对大皂角的本草考证、主要化学成分以及药理作用进行综述，以期为大皂角进一步的开发和合理应用提供参考。 |
| 关键词: 大皂角 本草考证 化学成分 药理作用 |
| DOI：10.11656/j.issn.1673-9043.2025.05.11 |
| 分类号:R284;R285 |
| 基金项目:国家自然科学基金项目（82274091）。 |
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| Research Progress on Herbal Textual Research，Chemical Compositions and Pharmacological Effects of Gleditsiae Sinensis Fructus |
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WU Xiwei1, LI Caixia1, YANG Dongyue1, OUYANG Huizi2, HE Jun1
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1.Tianjin University of Traditional Chinese Medicine, Tianjin 301617;2.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
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| Abstract: |
| Gleditsiae sinensis fructus is a traditional Chinese medicine，rich in chemical compositions such as triterpene saponins，flavonoids，organic acids，lignans，amino acids and other chemical compounds，which possess a wide range of biological activities，including antitumor，antioxidant，anti-hyperlipidemic，and anti-HIV activities. It is commonly used clinically for bronchial asthma，bronchiectasis and other lung diseases. In this paper，herbal textual research，the main chemical constituents and the pharmacological effects of Gleditsiae sinensis fructus are reviewed，in order to provide a theoretical basis for the further development and application of Gleditsiae sinensis fructus. |
| Key words: Gleditsiae sinensis fructus Herbal textual research Chemical compositions Pharmacological effect |
