中医非药物疗法临床研究年度证据分析（2024年）

Annual evidence analysis of clinical esearch on traditional Chinese medicine non-pharmacological therapy（2024）

关键词:  中医非药物疗法  随机对照试验  证据分析  针灸临床证据库

Key words:  traditional Chinese medicine non-pharmacological therapy  randomized controlled trial  evidence analysis  acupuncture and moxibustion clinical evidence database

摘要:

[目的] 系统检索2024年度发表于中英文医学期刊的中医非药物疗法随机对照临床试验（RCT），对临床研究证据进行阶段性总结及质量评估，旨在为后续研究设计与循证决策提供参考。[方法] 基于针灸临床证据数据库（ACU-CED）系统，全面获取2024年度中医非药物疗法RCT文献，依托ACU-CED系统的结构化提取与质量评价等模块进行统计分析，运用ECharts可视化系统进行展示。[结果] 共纳入2 243篇RCT文献，其中中文2 196篇、英文47篇，累计样本量超过20万人次。研究覆盖全国34个省市及多个国家，疾病分布以肌肉骨骼系统、神经系统及消化系统疾病居多，卒中、颈椎病及失眠为主要研究热点。干预措施以针灸、艾灸、推拿、耳穴贴压及经皮电刺激等为主，加载或联合治疗趋势显著。整体研究质量较以往年度有所提升，但报告规范化和试验注册仍需加强。[结论] 2024年度中医非药物疗法RCT数量较往年增长，研究领域更加多元。尽管方法学质量与报告规范较前有所改善，但仍存在随机化、盲法及注册环节薄弱等问题。未来应加强研究者培训与多中心合作，推动研究设计规范化、结果报告透明化及证据转化应用，为中医非药物疗法的临床推广与国际化提供更坚实的循证支撑。

Abstract:

[Objective] The system retrieves randomized controlled clinical trials（RCT） of traditional Chinese medicine non-pharmacological therapies published in Chinese and English medical journals in 2024，summarizes the clinical research evidence in stages and evaluates its quality，aiming to provide reference for subsequent research design and evidence-based decision-making. [Methods] Based on the acupuncture and moxibustion clinical evidence database（ACU-CED） system，comprehensive access to 2024 Chinese medicine non-drug therapy RCT literature，statistical analysis based on the structural extraction and quality evaluation modules of the ACU-CED system，and display using ECharts visualization system. [Result] A total of 2 243 randomized controlled trials（RCTs） were included，including 2 196 in Chinese and 47 in English，with a cumulative sample size of over 200 000 people. The study covers 34 provinces，cities，and multiple countries across the country，with diseases mainly affecting the musculoskeletal，neurological，and digestive systems. Stroke，cervical spondylosis，and insomnia are the main research hotspots. The intervention measures were mainly acupuncture and moxibustion，moxibustion，massage，auricular point sticking and transcutaneous electrical stimulation，and the trend of loading or combined treatment was significant. The overall research quality has improved compared to previous years，but the standardization of reports and registration of trials still need to be strengthened. [Conclusion] The number of RCT for traditional Chinese medicine non-pharmacological therapies in 2024 has increased compared to previous years，and the research fields are more diverse. Although the quality of methodology and reporting standards have improved compared to before，there are still issues such as randomization，blinding，and weak registration processes. In the future，it is necessary to strengthen researcher training and multi center cooperation，promote standardized research design，transparent result reporting，and evidence transformation and application，and provide more solid evidence-based support for the clinical promotion and internationalization of non-pharmacological therapies in traditional Chinese medicine.