| 本文已被：浏览 195次 下载 45次 |
码上扫一扫！ |
|
|
| “宣肺清热，化瘀通络”法联合阿奇霉素治疗小儿肺炎支原体肺炎疗效观察 |
|
李焕敏1, 陆丘1,2, 马莉婷1, 孙丹1, 韩耀巍1, 梅沄铮1, 王慧哲1, 李新民1
|
|
1.天津中医药大学第一附属医院, 中医国家临床医学研究中心, 天津 300381;2.贵州中医药大学第一附属医院, 贵阳 550001
|
|
| 摘要: |
| [目的] 该研究采用回顾性队列研究的方法，评估以“宣肺清热、化瘀通络”理论为指导的中药方剂联合应用阿奇霉素在小儿肺炎支原体肺炎（MPP）治疗中的临床疗效。[方法] 该研究以2018年1月—2019年10月为观察时段，纳入在天津中医药大学第一附属医院儿科住院治疗的1 567例MPP患儿为研究对象。阿奇霉素作为常规基础治疗，按照中药处方治疗法则的不同，将使用依据“宣肺清热、化瘀通络”法开处的中药汤剂的患儿纳入暴露组，将使用依据常规中药治法开处的中药汤剂的患儿纳入非暴露组，观察以“宣肺清热、化瘀通络”法为指导的中西医结合方案对小儿MPP的治疗效果。[结果] 在临床痊愈率、中医证候痊愈率、完全退热时间、咳嗽缓解时间、并发症发生及重症MPP临床痊愈率上暴露组均优于非暴露组。[结论] “宣肺清热、化瘀通络”法联合阿奇霉素能有效提高MPP患儿临床疗效，减少并发症及重症的发生。 |
| 关键词: 宣肺清热、化瘀通络法 回顾性队列研究 肺炎支原体肺炎 临床疗效 |
| DOI：10.11656/j.issn.1673-9043.2026.02.05 |
| 分类号:R563.1 |
| 基金项目:天津市中医药重点领域科研项目（2018009），天津市科学技术局多元投入基金项目重点项目（21JCZDJC01130），国家中医药管理局中西医结合与少数民族医药司项目（2023368）。 |
|
| Treatment of mycoplasma pneumoniae pneumonia in children with the combination of “Xuanfei Qingre， Huayu Tongluo” method and azithromycin |
|
LI Huanmin1, LU Qiu1,2, MA Liting1, SUN Dan1, HAN Yaowei1, MEI Yunzheng1, WANG Huizhe1, LI Xinmin1
|
|
1.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine, Tianjin 300381, China;2.First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang 550001, China
|
| Abstract: |
| [Objective] This study adopted a retrospective cohort study method to evaluate the clinical efficacy of a traditional Chinese medicine（TCM） formula guided by the theory of“Xuanfei Qingre，Huayu Tongluo”in combination with azithromycin for the treatment of Mycoplasma pneumoniae pneumonia（MPP） in children. [Methods] This study observed the period from January 2018 to October 2019 and included 1，567 children with MPP hospitalized in the Pediatrics Department of the First Teaching Hospital of Tianjin University of TCM as the research subjects. On the basis of routine treatment with azithromycin，according to the different treatment rules of TCM prescriptions，the children who used TCM decoction prescribed according to the method of“Xuanfei Qingre， Huayu Tongluo”were included in the exposure group；the children who used the TCM decoction according to the conventional TCM treatment were included in the non-exposure group. The clinical efficacy of the method of “Xuanfei Qingre，Huayu Tongluo”on children with MPP were observed. [Results] In terms of clinical cure rate， TCM syndrome cure rate，complete fever resolution time，cough relief time，incidence of complications，and clinical cure rate of severe MPP，the exposed group outperformed the non-exposed group. [Conclusion] The combination of “Xuanfei Qingre，Huayu Tongluo”method and azithromycin can effectively improve the clinical efficacy of MPP children，reduce the occurrence of complications and severe illness. |
| Key words: “Xuanfei Qingre,Huayu Tongluo”method retrospective cohort study Mycoplasma pneumoniae pneumonia clinical efficacy |
