| 摘要: |
| [目的]观察中西医结合治疗慢性肾功能衰竭伴继发性甲状腺旁腺功能亢进骨病的临床疗效。[方法]选取本院2016年1-6月收治的80例慢性肾功能衰竭伴继发性甲旁亢骨病临床稳定期患者，将其按照随机数字表法随机分为观察组和对照组，每组40例，对照组给予常规西药进行补钙，纠正酸中毒和水、电解质紊乱，降低血磷等治疗，观察组在对照组基础上给予补肾健骨方药进行治疗，1个月为1个疗程，两组均治疗3个疗程，观察治疗前后甲状旁腺素、碱性磷酸酶、钙、磷、血清肌酐、血尿素氮的变化。[结果]观察组和对照组两组患者血清钙水平及总体症状明显改善，观察组血清钙水平较对照组升高，血磷水平较对照组降低，总体症状较对照组明显改善，差异有统计学意义。[结论]在常规西药基础上配合补肾健骨方药治疗慢性肾功能衰竭可以有效升高血清钙以及降低血磷水平，改善患者的整体症状，提高其生活质量，且未见明显不良反应，值得临床推广。 |
| 关键词: 慢性肾功能衰竭伴继发性甲状腺旁腺功能亢进骨病 中药 血钙 补肾健骨 |
| DOI：10.11656/j.issn.1672-1519.2017.06.06 |
| 分类号:R692.5 |
| 基金项目: |
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| Clinical curative effects of chronic renal failure with secondary hyperparathyroidism of bone disease |
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LIU Mei-na1, MA Jian2
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1.Heilongjiang University of Chinese Medicine, Harbin 150040, China;2.The First Affiliated Hospital Heilongjiang University of Chinese Medicine, Harbin 150040, China
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| Abstract: |
| [Objective] To observe the clinical curative effects of chronic renal failure with secondary hyperparathyroidism of bone disease. [Methods] From January 2016 to June 2016 in our hospital 80 cases of chronic renal failure with secondary hyperparathyroidism of bone disease were selected, and randomly divided into an observation group and a control group(40 cases in each group).The control group was given conventional western medicine for filling calcium, correct acidosis and water electrolyte disturbances, reduce blood phosphorus treatment,while the observation group was treated by Bushen Jiangu decoction on the basis of the therapy in the control group with one month as a period of treatment, and two groups had three periods of treatment. Before and after treatment parathyroid hormone, alkaline phosphatase, calcium, phosphorus, serum creatinine, blood urea nitrogen were observed and compared. [Results] Serum calcium levels and overall symptoms in two groups were improved significantly, serum calcium levels in the observation group were higher than the control group, the blood phosphorus levels were declined than the control group, patients with general symptoms obviously were improved than the control group, the difference was statistically significant. [Conclusion] On the basis of conventional western medicine,using Bushen Jiangu decoction can effectively increase the serum calcium and decline phosphorus levels, improving the overall symptoms of patients and the quality of life, and no obvious adverse reaction and is worthy of clinical promotion. |
| Key words: chronic renal failure with secondary hyperparathyroidism of bone disease Chinese medicine serum calcium Bushen Jiangu decoction |
