| 摘要: |
| [目的] 应用Citespace和VOSviewer可视化软件探索槲皮素与心血管疾病相关领域的研究现状、热点及前沿。[方法] 检索Web of Science（WOS）核心合集数据库，运用Citespace6.1.R3和VOSviewer1.6.18软件对作者、共被引作者、国家、机构、期刊、共被引文献和关键词进行文献计量分析，并绘制相关可视化图谱。[结果] 共纳入897篇SCI文章。发文量和引文量呈现指数级增长态势。发文量最高的作者为Croft KD，引文量最高的作者为Egert S，最高产国家是中国，最高产机构是马什哈德医科大学。研究热点集中在血脂异常、动脉粥样硬化、抗氧化、抗炎、血管细胞黏附分子-1（VCAM-1）、有丝分裂原激活蛋白激酶（MAPK）信号通路、中草药和生物利用度方面。防治代谢综合征、MAPK通路、抗氧化和抗炎机制代表了该领域未来的研究趋势。槲皮素对肠道微生物影响的研究可能会成为未来一个新兴学术前沿领域。[结论] 本研究通过文献计量学分析从多个维度确定了槲皮素在心血管疾病应用中的研究热点和趋势，为未来的研究方向和科学决策提供了参考与借鉴。 |
| 关键词: 槲皮素 心血管疾病 Citespace VOSviewer 文献计量学 |
| DOI：10.11656/j.issn.1672-1519.2024.04.13 |
| 分类号:R714.252 |
| 基金项目:国家自然科学基金项目（82374421）；北京市自然科学基金项目（7232311）；北京市科技计划课题（Z19110 0006619025）；中国中医科学院科技创新工程重大攻关项目（CI2021A00921）。 |
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| Visual analysis of research hotspots and trends of quercetin for cardiovascular diseases |
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YANG Yingtian1,2, LYU Qianyu1, WU Qian1, LI Lanlan1, YE Xuejiao1, WANG Shihan1
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1.Department of Cardiovascular Internal Medicine, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;2.Faculty of Clinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
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| Abstract: |
| [Objective] To explore the current status，hotspots，and frontiers of research on quercetin for cardiovascular diseases using Citespace and VOSviewer software. [Methods] We retrieved the Web of Science Core Collection database and used Citespace 6.1.R3 and VOSviewer 1.6.18 to conduct bibliometric analysis of authors，co-cited authors，countries，institutions，journals，co-cited literature，and keywords. [Results] A total of 897 SCI articles were included. The number of publications and citations showed exponential growth. The author with the highest publications was Croft KD，the author with the highest citations was Egert S，the most prolific country was China，and the most prolific institution was Mashhad University of Medical Sciences. Research hotspots focus on dyslipidemia，atherosclerosis，antioxidant，anti-inflammatory，vascular cell adhesion molecule-1（VCAM-1），mitogen-activated protein kinase（MAPK） signaling pathway，herbal medicine，and bioavailability. The prevention and treatment of metabolic syndrome，MAPK signaling pathway，and antioxidant and anti-inflammatory mechanisms represent future research trends in this field. The study of the effects of quercetin on gut microbes may become an emerging academic frontier in the future. [Conclusion] This study identified hotspots and trends on quercetin research in cardiovascular field from multiple dimensions through bibliometric analysis，providing references and implications for future research directions and scientific decisions. |
| Key words: quercetin cardiovascular disease Citespace VOSviewer bibliometrics |
