国医大师李佃贵教授基于“中虚-浊阻-毒生”论治溃疡性结肠炎经验探析

Exploration of Professor LI Diangui，a master of traditional Chinese medicine，on the treatment of ulcerative colitis based on the theory of “deficiency in the middle jiao，turbidity obstruction，and toxin generation”

关键词:  溃疡性结肠炎  脾胃  浊毒  病机  经验

Key words:  ulcerative colitis  spleen and stomach  turbidity  pathogenesis  experience

摘要:

溃疡性结肠炎是常见的消化系统疾病，其存在一定的癌变风险。国医大师李佃贵教授根据多年临床经验，从“中虚-浊阻-毒生”的整体动态病机变化出发，探讨溃疡性结肠炎的病因病机及诊疗，认为中气虚损是发病之本，浊蕴肠腑是病变基础，久聚成毒是病机关键。据此，李佃贵教授多应用益气健脾、补虚固本，清热利湿、调和气血，化浊解毒、涩肠止泻等治则治疗溃疡性结肠炎，疗效显著，为临床诊疗提供参考。

Abstract:

Ulcerative colitis is a common digestive system disease，carries a certain risk of cancer. Based on years of clinical experience，Professor LI Diangui，a master of traditional Chinese medicine，explores the etiology，pathogenesis，diagnosis，and treatment of ulcerative colitis from the holistic and dynamic pathological perspective of “deficiency in the middle jiao，turbidity obstruction，and toxin generation”. He believes that deficiency of middle jiao qi is the root cause of the disease，turbidity accumulation in the intestines is the pathological basis，and prolonged accumulation leading to toxin formation is the key to the pathogenesis. Professor LI Diangui clinically applies treatment principles such as invigorating qi and strengthening the spleen，tonifying deficiency and consolidating the root，clearing heat and draining dampness，regulating qi and blood，resolving turbidity and detoxifying，and astringing the intestines to stop diarrhea，achieving remarkable therapeutic effects and providing valuable references for clinical diagnosis and treatment.